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"The landscape of metabolic brain alterations in Alzheimer's disease". Congrats to co-first authors @richreckons and Matthias Arnold. Thanks to everyone involved! #metabolomics #Alzheimers alz-journals.onlinelibrary.wiley.com/doi/10.1002/al…

The brains of individuals with Alzheimer's show dramatic metabolic changes linked to memory loss, a disease symptom, according to a new study led by Dr. Jan Krumsiek of WCM Englander Institute for Precision Medicine. bit.ly/3KZhwk8

Congratulations to our WCM Englander Institute for Precision Medicine colleagues Drs. Jan Krumsiek (Jan Krumsiek), Karsten Suhre (Karsten Suhre), Richa Batra, Kelsey Chetnik, Mustafa Buyukozkan, and Elisa Benedetti for their work on this paper, with Weill Cornell Medicine colleagues! #omics #COVID19 #ARDs #PrecisionMedicine

We are hiring! The Krumsiek Lab Weill Cornell Medicine is looking for two PostDocs with experience in omics data analysis who are interested in driving our collaborations in the context of Cancer and Alzheimer's disease. Job details and info on how to apply at krumsieklab.org/join-us.

Excited to share new work with Jan Krumsiek led by Elisa Benedetti+Eric Minwei Liu+Cerise Tang. It represents our two-fold efforts to make amends for TCGA’s omission of metabolomics, and to learn something exciting about coregulation of genes and metabolites biorxiv.org/content/10.110…

Our new method for statistical regression with missing values without the need for imputation. Check it out! Mustafa Buyukozkan #metabolomics mdpi.com/2218-1989/13/1…

The latest publication by Dr. Jan Krumsiek (Jan Krumsiek) from WCM Physiology & Biophysics and the WCM Englander Institute for Precision Medicine, with Dr. Richa Batra, "Urine-based multi-omic comparative analysis of #COVID19 and bacterial #sepsis-induced ARDS," in Molecular Medicine - Journal! #PrecisionMedicine molmed.biomedcentral.com/articles/10.11…

You can now track over 1,000+ molecules in a single drop of blood with microsampling. Stanford University professor & my iollo co-founder Michael Snyder, PhD's lab just published this in Nature Biomedical Engineering. At iollo we're making this test accessible to everyone.

Introducing iollo's GPT-4 companion - your personalized wellness partner. Answer a few questions, let it analyze & create a tailored plan, and track your progress via chat interface. Try it out here: health.iollo.com

Come join our team at #WCM! We're looking for a software developer to support our multi-omics analysis framework. #SoftwareDeveloper #R #Python #GitHub #coding #multiomics krumsieklab.org/join-us

Very pleased to share the first of two new papers from our group to drop. This one is driven by Elisa Benedetti, Eric Minwei Liu, and Cerise Tang , a joint effort by my group and the Jan Krumsiek lab nature.com/articles/s4225…

Dr. Jan Krumsiek (Jan Krumsiek), from the WCM Inst. for Comp. Biomedicine and WCM Englander Institute for Precision Medicine, just published "A multimodal atlas of tumour metabolism reveals the architecture of gene–metabolite covariation," in Nature Metabolism. krumsieklab.org nature.com/articles/s4225…

An atlas that catalogues gene activity and the levels of small molecules called metabolites in tumor samples offers a new way of identifying the deep mechanisms of cancer, according to new research led by Ed Reznik of MSK and Jan Krumsiek of Weill Cornell Medicine. bit.ly/3O3o7NL

Our lab has released the blood metabolomic profiles and clinical annotations of 580 patients from the Weill Cornell EDRN Prostate Cancer cohort. This data is now accessible to scientists and researchers. nature.com/articles/s4159…

medrxiv.org/content/10.110… - new preprint from a close collaboration with Jan Krumsiek's lab where we show that blood levels of bioenergetic markers (acylcarnitines) group ADNI participants by AD symptoms and biomarker profiles. (1/7)

Excited to share our new paper out in PNASNews pnas.org/doi/10.1073/pn… on cysteine susceptibility in #glioma. This was a long effort over years with Cantley Lab @Lnpalma Isaiah Yim Nayah Bullen Daniel Barnett Jan Krumsiek Olivier Elemento among others Weill Cornell Neurology Weill Cornell Medicine Meyer Cancer Center

New paper out in npj Metabolic Health and Disease! We profiled the molecular impacts of the ketogenic diet simultaneously in plasma and CSF (a first!), showing how dietary changes influence the brain's metabolic environment and Alzheimer's disease risk: doi.org/10.1038/s44324…

Excited to share 'AutoFocus,' our new tool for the unbiased exploration of complex multi-omics datasets. nature.com/articles/s4200…

This is now out in Nature Communications - nature.com/articles/s4146… Thanks to the reviewers, there are some nice extensions to the preprint version, including a simulated trial that suggests targeting bioenergetics in Alzheimer's has significant therapeutic potential.

Excited to see newsroom coverage of our latest paper on bioenergetic age in Alzheimer's disease! Great collaboration with Matthias Arnold. news.weill.cornell.edu/news/2025/03/l…