🔥The 9th Round of Easy Loan, Earn $40 Reward is in progress❗️ ⏰ Promotion Period: January 15th - Feburary 15th, 2025 👉 Register now and check more details at gate.io/campaigns/358

Illustration of von Brunn nests in upper tract...tend to be smaller and either closely aligned or horizontally / linearly aligned to overlying urothelium - can occasionally present a diagnostic dilemma, esp. in small specimens, as highlighted here: pubmed.ncbi.nlm.nih.gov/12960809/ #gupath

Metaplastic carcinomas of the breast Therapy considerations Dr. Varga #USCAP25 #pathology #PathX

Esophagus The difference between intramucosal carcinoma and high grade dysplasia is not as critical as it was before. They are going to be treated the same way, with endoscopic erradication therapy (see pic 4) Dr. Voltaggio #USCAP25 #pathology #pathX

Best way/more efficient way to process a serous/cavity fluid -Create one thinprep slide -The residue should all go to a cell block Thinprep is a filtration process and it gets you a cleaner sample Dr. Siddiqi #USCAP25 #pathology #PathX

Mesothelioma in situ (MIS) They can present as a surface proliferation, flat or papillary lesion with no stromal invasion and loss of BAP-1 (or loss of Merlin or Mtap) When to think of MIS -Recurrent pleural effusion or ascitis -Unilateral pleural effusion -Can be bland but

Lung cancer Landscape of genomic alterations in NSCLC with corresponding therapeutic options (2024, ongoing and evolving topic) Dr. Siddiqi #USCAP25 #pathology #pathX

Cytology Gastric Adenocarcinoma Dr. Siddiqui #USCAP25 #pathology #PathX #PathBoards

Cytology Breast Adenocarcinoma Dr. Siddiqui #USCAP25 #pathology #PathX #Pathboards

Screening pap smear. What would you call these cells? 🤔 A) High grade squamous lesion (HSIL) B) Atypical glandular cells (AGC) C) Benign endometrial cells D) Tubal metaplasia #CytoPath #Pathology

Cytology Metastatic Mullerian Serous Carcinoma Dr. Siddiqui #USCAP25 #PathX #pathology #PathBoards

Mesenchymal tumors of pancreas-RARE -Benign: Most common Schwannoma -Malignant: Most common leiomyosarcoma Always rule out a metastasis and undifferentiated/spindle cell carcinoma first Dr. Agostini-Vulaj #USCAP25 #pathology #PathX

Mesenchymal neoplasms of Gallbladder and Billiary tract -Granular cell tumor -Schwannoma -IMT Dr. Agostini-Vulaj #USCAP25 #PathX #pathology

Lymphatic malformation (known previously as cystic hygroma or lymphangioma) Macrocystic (>= 1 cm) they can be treated with sclerosing agents Microcystic can be treated with surgery or combination Dr. Gupta #USCAP25 #pathology #PathX

Breast Differences between Invasive Lobular Carcinoma and Invasive Ductal Carcinoma Dr. Sahin #USCAP25 #pathology #PathX

Challenges in staging Invasive Lobular Carcinoma (ILC) Small mass detected on mammogram. Additional imaging showed architectural distorsion. Patient decided for mastectomy (pic 1) Serial sections show two ill-defined noncontiguous lesions away from primary tumor (pic 2)

Breast-Invasive Lobular Carcinoma Higher risk of positive margins than invasive ductal carcinoma (IDC) ILC had twice the risk of positive margins in segmental resections Dr. Sahin #USCAP25 #pathology #PathX

Breast Histologic Variants of Invasive Lobular Carcinoma (ILC) -Many of these variants coexists and could be difficult to separate one from the other New variants (WHO 6th edition) -ILC with extracellular mucin -ILC with solid papillary growth Dr. Sahin #USCAP25 #pathology

IHC features of Invasive Lobular Carcinoma (ILC) Dr. Sahin #USCAP25 #PathX #pathology

44F with hemithyroidectomy. Supplied history was ‘thyroidectomy’. 🙄. 11mm encapsulated nodule. No capsular or vascular invasion.

Breast-Invasive lobular carcinoma Challenges in diagnosis Alveolar variant of ILC can mimic LCIS, important to run IHC (p63, SMMHC) to confirm diagnosis Dr. Sahin #USCAP25 #pathology #PathX