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Data from the new TargetD trial suggests that prior vitamin D trials were flawed: news-medical.net/news/20231113/… Many people, even professionals, still think vitamin D was a false profit that was disproven by big RCTs. This view is very flawed, for several reasons. A brief history:

The promise of machine learning approaches to capture cellular senescence heterogeneity - Nature Aging buff.ly/4e12Jm9

Online now!✨RESEARCH: harnessing age-related changes to the spatial organization of chromatin and epigenetic marks, ‘ImAge’ establishes an imaging-based biomarker of aging nature.com/articles/s4358… rdcu.be/dSmEJ

Once again, ☕️☕️☕️ and caffeine linked with reduced cardiometabolic diseases academic.oup.com/jcem/advance-a… From UK Biobank, >170,000 participants

WashU research funding exceeds $1 billion for first time source.washu.edu/2024/09/washu-…

‼️Go talk with Ariella Coler-Reilly🏳️‍🌈 from @WashU_BMD if want to learn about her elegant approach to discover drivers of aging!! 🤩 #ASBMR2024 Roberto Civitelli Scheller Lab

Now online! CSF proteomics identifies early changes in autosomal dominant Alzheimer’s disease dlvr.it/TDpmPR

Hi folks! Check out my webinar via Foresight Institute where I present my research on developing a new gene therapy delivery system that can circumvent preexisting immunity to enable cures - and announce the launch of my new spinoff Cathedral Therapeutics Inc. youtu.be/JCRrMhCItgo

Can we use CRISPR screens to identify genes that drive neural stem cell aging? Super excited to see this work published nature! Huge congrats to Tyson @ruetz_tyson, Angie Pogson, Chloe Kashiwagi, and all authors! Great collaboration with Michael C Bassik! nature.com/articles/s4158…

Brilliant study on the functions of senescent cells, using p16 as a marker, showing that in mice different types of senescent cells play beneficial or detrimental roles. Can we finally stop calling senescent cells zombie cells? cell.com/cell/fulltext/…

Congrats to Shift Bioscience on their $16M seed to develop epigenetic reprogramming for aging! Fun fact: Daniel / Shift Bio was the first company we invested in at Healthspan Capital. The team is extremely relentless, scrappy, super smart. endpts.com/shift-bioscien…

Longevity biotechnology: bridging AI, biomarkers, geroscience and clinical applications for healthy longevity Yu-Xuan Lyu (Lu), PhD, Qiang Fu, Dominika Wilczok, Kejun (Albert) Ying, The Scheibye-Knudsen Lab, Daniela Bakula and coauthors including labs on X: Aaron King, Antebi Lab, Alexey Moskalev,

Highly recommend the Apte Lab for incoming PhD students at WashU! Thank you for everything, Raj!

The peer-reviewed version of expansion in situ genome sequencing is now out in Science! The news is bittersweet – when we first revealed this last September, I never guessed it would be my final paper in academia, but a lot has changed. A few parting thoughts:

I'm thrilled to share our new study out in Nature Medicine! We show that a blood test can estimate how aged or youthful one’s organs are and that these organ ages predict future disease and lifespan. Final paper from my PhD in the Tony Wyss-Coray lab. 🧵1/12 🔗 nature.com/articles/s4159…

NEW: No technology currently exists to repair damaged brain tissue and fully restore lost function. FRONT aims to enable millions with what is considered permanent brain damage to regain lost functions, including motor control, vision, and speech. arpa-h.gov/news-and-event…