Excited to have this work finally published on Nature Communications. With the Trcek lab Johns Hopkins University, Silvi Rouskin and Thirumalai Lab @ UT Austin labs, we show that RNA structure impedes intermolecular base pairing in germ granule. nature.com/articles/s4146…

Polysomes and mRNA control the biophysical properties of the eukaryotic cytoplasm: Cell Reports cell.com/cell-reports/f…

Rethinking RNA-binding proteins: Riboregulation challenges prevailing views: Cell cell.com/cell/fulltext/…

Our work on genetic variants that affect RNA stability is out in Nature Genetics! We present the RNAtracker computational pipeline, which can distinguish between transcriptionally- vs. stability-mediated regulation of gene abundance. bit.ly/42aihk2 (1/n)

Large language models are reshaping the way we do science, but how well do they actually understand plant molecular biology? ➡️We created MoBiPlant to answer this. 📝Preprint: biorxiv.org/content/10.110… 💾Dataset: huggingface.co/datasets/manuf… (Thread below)

I am excited to share my graduate work in David M. Sabatini and Dave Bartel’s labs. Since their discovery, we have known lysosomes possess RNase activity; however, their substrates were not known. Surprisingly we find specific RNAs are targeted for degradation! biorxiv.org/content/10.110…

Happy to share our new preprint: Subcellular mRNA localization patterns across tissues resolved with spatial transcriptomics: biorxiv.org/content/10.110… We utilize VisiumHD to extract intra-cellular mRNA polarization patterns in epithelial tissues.

Online Now: Rapid UPF1 depletion illuminates the temporal dynamics of the NMD-regulated human transcriptome dlvr.it/TN0GcP

Happy to share that we identified a conserved 17kb long-range RNA-RNA interaction in SARS-CoV-2 that impacts virus fitness. Congratulations to all the authors! nature.com/articles/s4146…

Our annual event at Norwich RNA Club: AI in RNA Biology. Great speakers! Please join us this Thursday at 2pm John Innes Centre Earlham Institute Alper Akay Wilfried Haerty Yiliang Ding Norwich RNA Club Norwich Research Park UEA

Now online! Sequencing-free whole-genome spatial transcriptomics at single-molecule resolution dlvr.it/TNPx48

🚨 New in JACS! We show that covalent probes can reveal druggable small-molecule pockets in RNA—validated by cryo-EM—and design compounds that inhibit SARS-CoV-2 by misfolding its RNA. Read paper here - Congrats to Amir, Sandra & Jielei 👏 🔗 doi.org/10.1021/jacs.5… Read 📷

Deep Learning for Biology, by Charles Ravarani & Natasha Latysheva A hands-on guide to applying deep learning across DNA, proteins, medical images, and more. Each chapter is a project-driven path into AI-powered biology—covering CNNs, transformers, GNNs, and autoencoders.

Why does the naked mole rat have the longest lifespan and healthspan of any rodent, nearly 40 years? A 30-year long mystery unraveled Science Magazine today! Its cGAS enzyme in cells has 4 missense mutations that upends its function, promoting DNA repair and suppressing

Congratulations to Huakun Zhang's group! #plantlncRNA

Online Now: Metabolic environment-driven remodeling of mitochondrial ribosomes regulates translation and biogenesis dlvr.it/TP6Tcj

I would strongly advise every American leader and policymaker to listen carefully to David R. Liu - the most important scientist and innovator of our lifetime and the person who invented both Base editing & Prime editing - the 2 top leading modalities of Gene editing, when he

✨ Happy to share that our work is now published in The EMBO Journal! ✨ Our fantastic collaboration between Moreno-Mateos Lab from Centro Andaluz de Biología del Desarrollo and BazziniLab from Stowers Institute. Take a look to our updated thread (1/14): embopress.org/doi/full/10.10…

Please take a look to this fantastic thread of Luis Hernández-Huertas leading this work from our lab that pioneers the use of CRISPR-RfxCas13d screenings to uncover new maternal regulators of early development in fish. More exciting screenings are coming with new factors, stay tuned! :)

Localized mRNAs and protein synthesis in cortical layer 1 biorxiv.org/content/10.110…