Since the discovery of CRISPR-Cas systems, people have wondered if a similar type of system exists in eukaryotes. Today, we report in nature the characterization of Fanzor, a eukaryotic RNA-guided system that can be reprogrammed for human genome editing. nature.com/articles/s4158…

A general thread on what Perturb-seq is, what it's good for, and how we managed to reduce its cost by an order of magnitude in our recent work: 1/33

Metabolites and RNA in a tissue section are profiled simultaneously go.nature.com/45Rms4l

So excited to come home to San Diego for cardiology fellowship!🫀🧬 UC San Diego Cardiology UC San Diego Cardiology Fellows

We are extremely proud to welcome our newly matched general cardiology fellows! Welcome to the UC San Diego Cardiology Fellows family! @HongJessica_ Emily Margolin, MD Rebecca Ocher Anna McDivit Mizzell, MD, FACC Harpreet Bhatia

Sudden ST changes on telemetry prompt a 12-lead ECG for a critically-ill patient who is intubated, sedated, and paralyzed. What would you do next? ja.ma/3Rc7YWh @HongJessica_

What would you do next? Your intubated ICU patient develops acute, diffuse ST elevations after neuromuscular blockade. Check out our JAMA Cardiology case Marcella Press MDPhD #ecg #CardioEd jamanetwork.com/journals/jamac…

Our latest nature paper is out! We show that transplanting mitochondria into endothelial cells boosts their ability to form blood vessels in ischemic tissues, with mitophagy as the key mechanism. A potential game-changer for vascular cell therapies. nature.com/articles/s4158…

Nature research paper: Temporal dynamics of the multi-omic response to endurance exercise training go.nature.com/3QtJ6Km

New publication nature from Dr. Kevin King and Dr. Van Ninh: Spatially clustered type I interferon responses at injury borderzones Eric Adler UC San Diego Cardiology Fellows UC San Diego Health Sciences nature.com/articles/s4158…

Incredibly exciting to see Dr. Hsue, brilliant physician scientist and woman, at the helm! 🙌🫀

Cool tech here, imagine the potential applications

Amazing capability of nanopore for amino acid sequencing

👏 👏 well deserved!

A cath conference gem from our first-year fellow Dr. Jessica Hong @HongJessica_

One man’s trash is another’s treasure! Very interesting concept.

Fascinating.

What's new with Lp(a)? In this review led by Alexander C. Razavi, we aimed to summarize the most recent research related to Lp(a), current therapeutic approaches and novel therapies. Jessica Hong, MD UC San Diego Cardiology UC San Diego Cardiology Fellows Family Heart Foundation ASPC link.springer.com/epdf/10.1007/s…

A new #UCSDCardiologyCases from Dr. Jessica Hong (Jessica Hong, MD)! 🏄‍♂️ Young man suffers a VF arrest while surfing. Pulled from the ocean, gets CPR, achieves ROSC. You get this ECG in the ED. What pattern is this, and what's your immediate plan? #CardioTwitter #ECG #FOAMed

Strong binders can be too clingy. This Baker lab paper engineers an off-switch for protein interactions.