"Hey what’s this funny donut 🍩 stuck on the crash cart?" It's a 🧲 magnet! We keep it there because it can be life-saving if applied over a pacemaker or ICD. A 🧵about magnets, pacemakers & ICDs. Some useful facts that everyone in an ICU ought to know. #FOAMcc #FOAMed 1/

#Takotsubo 🫀😀

A heart muscle cell photographed through a microscope by Abigail Neininger-Castro, PhD. #CellBiology

🫀#Bloodflow through the #heart 🫀

Heart With Coronary Vessels 🫀

To the last beat #hearttransplantation 🫀

Check out the most comprehensive proteomic study profiling plasma membrane proteins on cardiovascular cells by our great collaborator @Gundrylab.

“Today, I will explain to my healthy transplanted heart why, in what may be a matter of days or weeks at best, she — well, we — will die.” Kiran Khush Maryjane Farr MD MSc, FACC FAST FHFSA FAHA Shelley Hall Dr Amanda Vest Jeff Teuteberg @ersied727 Luise Holzhauser, MD Palak Shah nytimes.com/2023/04/18/opi…

Honored to have worked with the NIH Clinical Center cardiology service, seeing some of the most memorable patients under great mentorship! #cardiology UA College of Medicine – Tucson

Thank you #EMC for the warm welcome in Florence and opportunity to present my PhD work #cardiacmuscle #cardiomyopathy

Enjoyed presenting my work from the NIH Clinical Center at ACP Arizona Chapter! #cardiology

Remembering the first woman to be awarded a Nobel Prize, the first individual to be awarded two Nobel Prizes and still today the only individual with two Nobel Prizes in two different scientific categories: Marie Skłodowska Curie. Curie was born #OnThisDay in 1867.

Two papers in nature describe the structure and conformation of myosin in the cardiac thick filaments and how it interacts with other proteins, such as titin and cMyBP-C, in mammalian hearts ($): doi.org/10.1038/s41569… Davide Tamborrini, @intein, Raúl Padrón #ResearchHighlight

We're celebrating the International Day of Women and Girls in Science! Let's look back on the life of Marie Skłodowska Curie: a Nobel Prize laureate who dedicated her life to science and became one of the world's greatest scientists. #WomenInScience #NobelPrize

Excited to share results from our collab with the Gregorio lab to understand neonatal dilated cardiomyopathy (Lmod2) through integration of mouse models, iPSCs, CRISPR gene editing, EHTs, calcium imaging, and transcriptomics Jessika Iwanski, MD PhD npj Journals rdcu.be/dT5TE

This project has been 5+ years in the making! I’m excited to finally share our work and I hope this research may lead to further advances in our understanding of genetic mutations leading to neonatal DCM🫀 npj Journals Jared Churko rdcu.be/dT3IL

💓 Using patient-specific hiPSC-derived #cardiomyocytes and a mouse model, Dr. Jessika Iwanski, MD PhD and scientists at University of Arizona discovered dysregulated actin-thin filament lengths and alterations in the serum response factor-dependent 🚦 signaling pathway. 🔗 go.nature.com/3XqUaup

We were awarded an institutional AHA award to train the next generation of undergraduates in Cardiovascular Drug Discovery. Undergrads, reach out to one of our mentors (Sakthivel Sadayappan, PhD, MBA Jared Churko Shanna Hamilton Samantha Harris Colson lab Granzier lab) to apply. Jon Pagtakhan

I still see manuscripts using expensive and unnecessary components to generate iPSC derived cardiomyocytes. Save research $ and only use base media (DMEM/F12 w/ HEPES) supplemented with 128 ug/mL AA2P following a Wnt modulator schedule (CHIR and IWR1). …rentprotocols.onlinelibrary.wiley.com/doi/10.1002/cp…

The protocol is also protein- and xeno- free making the CMs less variable and more applicable for drug discovery and regenerative medicine purposes. Center for Innovation in Brain Science Gootter-Jensen Foundation UA College of Medicine – Tucson BIO5 Institute Jessika Iwanski, MD PhD