Is it BCP? Cubane? Oh no, it is O-[2.2.2] - ideal Ph-bioisoster! ChemRxiv: bit.ly/3XAJKY1

Check out our latest Nature Chemistry paper on the catalytic undirected borylation of tertiary C–H bonds, done in collaboration with Enamine Ltd 🇺🇦 and JanssenUS! Congratulations Isaac Yu and @JanssenEMEA! nature.com/articles/s4155…

The final version of this work has appeared in J. Am. Chem. Soc. today: pubs.acs.org/doi/full/10.10…

Check out our newest publication in Nature Synthesis about O-, N- and C-bicyclopentylation using thianthrenium reagents! nature.com/articles/s4416… Congrats to all involved! (Open access)

Congratulations to Brandon Wright and Michael Black and our collaborators at Janssen on the publication of a skeletal editing approach to build bicyclopentanes from aza-bicyclohexanes in JACS! pubs.acs.org/doi/pdf/10.102…

Ed Anderson Group 🇺🇦 is delighted to share our Perspective on the beautiful BCP framework in JACS Au. Congratulations Bethany Shire on this article! See: Conquering the Synthesis and Functionalization of Bicyclo[1.1.1]pentanes pubs.acs.org/doi/10.1021/ja…

Cool!

The deadline to apply for the SURF program this summer is around the corner! Don't miss your chance to learn from renowned faculty and dig into the innovative science at UTSW. Learn more and apply at bit.ly/3yeoQDj

Very pleasant collaboration with our industry colleagues from Merck Rohan Merchant Si-Jie(SJ) Chen and Novartis nɹnznʎ ! Really fantastic alkyl amine library via HTE implementation done by Si-Jie Si-Jie(SJ) Chen

Reaction Paradigms that Leverage Cycloaddition and Ring Strain to Construction Bicyclic Aryl Bioisosteres from Bicyclo[1.1.0]butanes (S. J. Sujansky and X. Ma) onlinelibrary.wiley.com/doi/10.1002/aj…

Three-dimensional saturated C(sp3)-rich bioisosteres for benzene nature.com/articles/s4157… A new review from Jet Tsien, Chao Hu, Rohan Merchant & Tian Qin (Qin Lab) from UT Southwestern Medical Center Merck

The final version of this work has appeared today in J. Am. Chem. Soc. A General Three-Component Alkyl Petasis Boron–Mannich Reaction | Journal of the American Chemical Society pubs.acs.org/doi/10.1021/ja…

Finally, RADICAL CROSS COUPLING without the exogenous REDOX. We disclose in ChemRxiv (chemrxiv.org/engage/chemrxi…) a broadly general platform for achieving transformations that normally required excess metallic or chemical reducing agents or photochemical setups (and their

So pleasant to participate in this amazing project and see it coming out!

Never imagine the hydroxylethylation in such a simple protocol and now it is there.

It is super excited to see one of my last projects in which I participated during my last months in UTSW come out: chemrxiv.org/engage/chemrxi…; Very excited to share our latest work on modular installation of persulfuranyls, SF5 in particular, with a series of bench-stable reagents.

This is a great collabotation with Dr. Renzhe Li Renzhe , Dr. Chang Liu, Dr. Chao Hu Chao Hu, Si-Jie(SJ) Chen, nɹnznʎ Rohan Merchant under the guidance and support from Qin Lab. Kudos to Dr. Renzhe Li Renzhe for driving this amazing project.

Super excited to share this toolbox and it's really a great collaboration with all of my colleagues!

Congrats to the SF5 team Renzhe Chao Hu in Qin Lab . N-SF5 substituted azetidines really enlarged novel chemical space with SF5 substitution and will provide a new type of isosteres for medicinal chemists!

Modular Access to N-SF5 Azetidines | Journal of the American Chemical Society UT Southwestern Medical Center pubs.acs.org/doi/10.1021/ja…