🔥The 9th Round of Easy Loan, Earn $40 Reward is in progress❗️ ⏰ Promotion Period: January 15th - Feburary 15th, 2025 👉 Register now and check more details at gate.io/campaigns/358

Thrilled to share our work on developing luminescent biosensors for SARS-CoV-2 antibody detection in Nature Biotechnology, led by Susanna Elledge and @xin_x_zhou! Excellent collaboration with Bryan Greenhouse, Cristina Tato, Taia Wang, Tim Henrich and others! nature.com/articles/s4158…

(1/4) Excited to share a bioRxiv from the lab of Jim Wells examining how immunosuppressive factors found in #tumors remodel the human CD8+ T cell surface #proteome (aka #surfaceome)! biorxiv.org/cgi/content/sh…

Super excited to share our latest work led by Shion Lim and Jie Zhou on targeting a proteolytic neo-epitope of CDCP1 in RAS-driven cancer, which can enable more effective & safer treatments with a conditional layer of disease-specific regulation! biorxiv.org/content/10.110…

Excited that I’ll be starting my own lab at Dana-Farber Chemical Biology Program and Dept. of BCMP Harvard Medical School in Spring 2022! Check out our new website: zhou-lab.org. Many thanks to my family, friends, collaborators, and mentors Michael Lin, MD PhD 🧬 Jim Wells for the unwavering support!

Excited to share a #bioRxiv preprint of collaborative work between Jim Wells and Robert Blelloch labs to develop a cell-tethered promiscuous biotinylator for the small-scale surface characterization of exosomes. Teamwork makes the dream work! biorxiv.org/content/10.110…

Read this week's Cancer Discovery #ResearchWatch Antibodies Against Cleaved CDCP1 Show Activity in RAS-Mutant Tumors by Shion Lim Jie Zhou Jim Wells UC San Francisco et al. bit.ly/3vfUVK7

Excited to announce that I will be joining the faculty Rockefeller University as an assistant professor in Jan 2023! My lab of computational molecular discovery will develop computational methods to bridge interesting chemistry to novel therapeutics. (1/3)

I'm excited to share our new cell surface N-terminomics technology to shed light on extracellular proteolysis ACS Central Science (pubs.acs.org/doi/10.1021/ac…)! Using #glycotime, @k_r_schaefer developed a glycan-tethered peptide ligase to capture proteolytic sites on living cells.

The very first preprint from our lab!! We repurposed a rapidly internalizing receptor TfR1 for membrane protein degradation. We show it works on single-pass, multi-pass, native and synthetic receptors. The overexpression of TfR1 on cancer cells offers potential tumor selectivity.

Thrilled to start my own lab at U Chicago in the Departments of Radiation & Cellular Oncology and Chemistry! Glad to also be a member of the Comprehensive Cancer Center. We're actively recruiting postdoc and RA with expertise in chemical biology and protein/antibody engineering.

voices.uchicago.edu/jzhoulab/resea… biologicalsciences.uchicago.edu/faculty/jie-zh… chemistry.uchicago.edu/faculty/jie-zh…

Huge shoutout to my mentors 🌟: Postdoc advisor Jim Wells (UCSF), PhD advisor @BingXu (Brandeis U), and undergrad advisor @YanZhang (Nanjing U). Immensely grateful for the unwavering support from my family, colleagues, friends, and collaborators!

Would you be surprised to learn that acid chlorides are not only compatible with biological research, in water mind you, but are in fact, AMAZING? Read on to see the answer… 1/n

Thrilled to share that my brilliant friend and previous colleague, Brandon Holmes, is now hiring for his new lab!

I'm thrilled and deeply honored to have been awarded the Cancer Research Foundation Young Investigator Award. This generous support means a great deal to me. A special thanks to Ralph Weichselbaum for the invaluable guidance and support.

Join us for upcoming info sessions to learn more about our PhD program in Chemistry at the University of Chicago! Details below. We are super excited about our vibrant research community, and you could be a part of it! Applications are also now open! chemistry.uchicago.edu/phd-applicatio…

Five questions with Weixin Tang go.nature.com/3BRldrz

🔥 Hot off the press: Ralph Weichselbaum, MD, and his team published a new study in nature demonstrating that high-dose radiation to primary tumors can unexpectedly promote tumor growth at metastatic sites. Ralph Weichselbaum Andras Piffko University of Chicago Radiation Oncology uchicagomedicine.org/forefront/canc…