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STARmap PLUS, combining high-res spatial transcriptomics with protein detection in the same tissue section, reveals a cellular map of disease progression in an #Alzheimer's mouse model New from Hu Zeng Jiahao Huang @PixelDream_cn Xiao Wang et al. nature.com/articles/s4159…

Our newest preprint led by an extraordinary neuroscientist Dr. Yujuan Su, reporting a complete neural circuit controlling airway hyperreactivity upon chronic allergen challenges.

Our group's "approach" for exploring interesting biology :) Harvard University MCB_Harvard HarvardBrainScience Marine Biological Laboratory (MBL) harvardmagazine.com/2023/03/featur…

A leptin-responsive hypothalamic circuit inputs to the circadian feeding network biorxiv.org/cgi/content/sh… #bioRxiv

New preprint alert from the lab! We identified a top-down slow breathing circuit that alleviates innate fear and anxiety without altering valence. Congratulations Dr. Jinho Jhang, and co-authors (Shijia Liu, and David O'Keefe). 1/3 biorxiv.org/content/10.110…

Goodbye Sunlab Xin Sun Lab and UCSD. I shall miss you all.

The Norwegian Academy of Science and Letters has decided to award the Abel Prize 2023 to Luis A. Caffarelli (UT Austin). #AbelPrize #AbelPrize2023

A team effort by Archana Venkataraman, James Bayrer and others UC San Francisco as well as the “down-under” gut gang VisceralPainResearch

Excited to see this work finally out! Can't imagine how a causal lunch meetup with Xiangyu Ren 任翔宇 turned into a multi-year collaboration where we identified the role of a spinal-parabrachial circuit in itch sensation! Thanks for the support from Martyn, Sung Han, and David Acton!

Where do new senses come from? In paired studies, we explore the structural basis of sensory receptor evolution in octopus and squid. @CoreyAHallard Wendy Valencia @RyanHibbs10 nature - nature.com/articles/s4158… - nature.com/articles/s4158…

Thrilled to share our latest work from Joe Ecker lab, using cutting-edge snmC-seq3 and snm3C-seq technologies to generate 301,626 methylomes and 176,003 mC+3C multiome profiles from 117 dissected regions throughout the adult mouse brain. (1/n) biorxiv.org/content/10.110…

So proud of ⁦@JosephMizgerd⁩ and ⁦Xin Sun Lab⁩ on their Scientific Axhievement Awards ⁦American Thoracic Society (ATS)⁩ !!

Extremely excited about the beta release of our brand-new Allen Brain Cell (ABC) Atlas web portal! Currently it includes an scRNA-seq dataset & a MERFISH dataset, each with ~4M cells, representing ~5200 clusters in the whole mouse brain. It is based on biorxiv.org/content/10.110….

A hunt, a surprise, and then clarity - Congrats to the team! Love 😍 it. Brain-Derived CCN3 Is An Osteoanabolic Hormone That Sustains Bone in Lactating Females biorxiv.org/content/10.110…

An absolutely gorgeous study from my college roommate Qijun Tang

In Chinese we call this “排面”

Newborn center with a mature lung! Xin Sun Lab

Scientists Discover a New Hormone that Can Build Strong Bones | UC San Francisco Thank you ⁦@LauraKurtzman⁩ for a great summary of team effort with ⁦@dr_ambrosi⁩ ucsf.edu/news/2024/07/4…

Wondering how neural circuits control allergen-induced airway hyperreactivity? Check out our latest study published on nature rdcu.be/dNmys

Scientists at UCSF Dept of Physiology have found a new way to control scar tissue in spinal cord injuries. This discovery could lead to therapies for better healing and scar management. tiny.ucsf.edu/gflXT7 UCSF School of Medicine