It's my pleasure to share with you are latest preprint demonstrating that #COVID-19 #mRNA #vaccine is re-adenylated in vivo. biorxiv.org/content/10.110… @IIMCB_Warsaw 1/n 🧵

Call for applications for PhD study and research on RNA chemistry in our group

Jeden billboard za Poznaniem, Wielkopolska. Brunet wieczorową porą, reż. Stanisław Bareja.

Measuring the steady state levels of mRNA is straight-forward, but measuring the rates governing the post-transcriptional fate of mRNAs - at a global scale - is far more challenging. This paper marks an important advance: nature.com/articles/s4159…

I have a postdoc position available in the chemistry of therapeutic oligonucleotides, application details below: my.corehr.com/pls/uoxrecruit…

It was only a matter of time: Phosphorus(V) gets "radicalized". Appearing today in ChemRxiv, access to new chemical space through the first stereocontrolled radical reactions of P(V): chemrxiv.org/engage/chemrxi… . Another awesome collaboration with the team at BMS.

Patrzcie no kto jedzie na marsz...😜😎😂 #Wszyscy4Go

Chemical Biology Fans! ….Glad to announce the IUPAC/13th International Symposium on Bioorganic Chemistry (ISBOC-13) iupac-isboc13.sg, Dec. 18-20, 2023, in Singapore, is now open for registration /abstract submission (Early Bird Deadline: Aug. 15th 2023). All are welcome!

A summary of our research on therapeutic mRNA published in Accounts of Chemical Research. Topics very timely lately :). Congratulations to Katalin Kariko and The Drew Weissman Lab !!! pubs.acs.org/doi/10.1021/ac… Uniwersytet Warszawski Joanna Kowalska

Degrade proteins, not your work schedule! A new method appearing today ChemRxiv (chemrxiv.org/engage/chemrxi…) simplifies access to molecular glues (like PROTACS) to save medicinal chemists valuable time. One-step access from cheap commercial materials, a trivial experimental setup,

Trinucleotide mRNA Cap Analogue N6-Benzylated at Site of Posttranscriptional m6Am Mark Facilitates mRNA Purification and Confers Superior Translational Properties In Vitro and In Vivo | JACS Uniwersytet Warszawski Dominika Nowis Jacek Jemielity Joanna Kowalska #RNA pubs.acs.org/doi/10.1021/ja…

Our latest paper featuring modified mRNA cap analog that increases the translational acitivity of mRNA has just been published in JACS. I am very proud of this work.

Biology-inspired modification of the 5' end of mRNA with high therapeutic potential. Probably the most important research in my life so far.

New Cover from Ella Maru Studio! Advanced mRNA Cap✊ This paper describes AvantCap - a chemical modification of messenger RNA 5' end that confers superior translational properties to mRNA. The design of AvantCap was inspired by a naturally occuring modification of mRNA cap - so

Dziękujemy wszystkim badaczkom i badaczom, którzy od wielu miesięcy wspierają #NCN! Budżet Centrum został zwiększony przez Kancelaria Premiera Ministerstwo Finansów Ministerstwo Nauki i Szkolnictwa Wyższego dzięki zaangażowaniu środowiska akademickiego.

Pleased to share our latest work: Chimeric cofactors enable methyltransferase-catalyzed prenylation: Chem cell.com/chem/fulltext/… Kudos to @EnzymeNicoCorn, Arne Hoffmann, Pulak Ghosh and x-less coathors 👏🤩👍

Come join our team! We have an opening for a research associate ("Ratsstelle"). Expertise in nucleotide chemistry and LC-MS is required. 👉 job-portal.lmu.de/jobposting/bb5…

🆕 Nasza droga na łamy nature była długa i wyboista. To pierwsza w XXI wieku publikacja w dziedzinie nauk o życiu w tym czasopiśmie wypracowana wyłącznie przez polskie jednostki – mówi o dzisiejszym artykule Andrzej Dziembowski IIMCB, Warsaw, Poland forumakademickie.pl/badania/nature…

Zespół kierowany przez prof. Jacka Jemielitego i dr hab. Joannę Kowalską z #UW opracował nowatorską metodę otrzymywania kolistych cząsteczek mRNA. Otwiera to nowe możliwości w projektowaniu stabilnych i skutecznych leków opartych na RNA. 🔗 uw.edu.pl/nowa-metoda-ch…

🚨We’re reviewing applications now!🚨 UF Scripps is hiring multiple faculty (Asst/Assoc/Full Prof) in RNA science as part of a major investment.📍Jupiter, FL – a gorgeous place to live + raise a family. Apply 👉 jobs.sciencecareers.org/job/670563/ Info 👉 wertheim.scripps.ufl.edu/rnamedicine RT to share!