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At the time when MD Anderson celebrated its 75th anniversary, President Biden attended our celebration and gave a talk about moonshot projects to conquer cancer. President Bush (Senior) was also present.

Prostate Cancer Facts: Happens: 1 in 8 men 90% can be diagnosed by PSA TX options for early disease: surgery or radiotherapy. Both have 10-year survival nearly 100% TX in metastatic disease hormone deprivation TX with others, 5-Y survival 30% Key: Early diagnosis and TX

Humbled and honored to be ranked as No. 1 poster in lung cancer this week.

President Biden’s PSA screening was done 10 years ago and never repeated until he had symptoms. For a prominent person with so much important responsibilities, should we screen for PSA? How should we individualize personal cancer screening?

Congrats ⁦Anirban Maitra⁩ for winning the Charles LeMaistre Award for Outstanding Achievement in Cancer Research ⁦MD Anderson Cancer Center⁩. You are an honorary member of #radonc for your collaboration and mentorship through the years!

Faculty Convocation speaker ⁦Dr. Glaucomflecken⁩ today ⁦MD Anderson Cancer Center⁩. Related his own cancer journey with humorous and poignant vignettes. #endcancer

Great tool to avoid recurrent laryngeal nerve damage with SBRT/SABR in lung cancer

Is chemo still needed? We need to know how many pts dropped out before surgery due to chemo toxicity.

ASCO 2025: Randomized HA-WBRT vs STS in 5-20 brain metastasis.

Neoadjuvant chemo/IO improved OS in operable NSCLC 5-OS: 95% in pts with cPR 75% in pts with negative ctDNA before surgery 10-20% can not have surgery after induction TX 10% has positive margin 10% needs post-OP RT Organ preservation options after Chemo/IO? cPR prediction?

This is a randomized study to validate our colleague David Qian’s published hypothesis: IO injection at early time of the day IO is better than later time. Can we hypothesize: Early time of SBRT/SABR delivery is better than later time of the day?

Structured exercise or healthy diet can improve overall survival in any populations with or without cancer. The challenge is how to motivate ourselves to change our habits, particularly for Americans (Top in medical expenses and inventions, but not in life expectancy).

Day 1 of PTCOG meeting in Buenos Aires, Argentina.

First phase III randomized study showed an improvement in overall survival with proton-based IMPT compared to photon IMRT in head and neck cancer. This was presented today during the The Particle Therapy Co-Operative Group (PTCOG) plenary session by Steven J. Frank, MD. The exciting data provides justification for IMPT.

Learn from negative studies: Negative studies should not be ignored. Negative studies may result from : A. futile hypothesis B. inappropriate study design: sample size endpoints the immaturity of technology PSPT vs IMPT: different generations of PT The Particle Therapy Co-Operative Group (PTCOG)

Joe Y Chang Shared PTCOG 2025 Phase III Data on IMPT vs. IMRT in Head and Neck Cancer Joe Y Chang The Particle Therapy Co-Operative Group (PTCOG) Steven J. Frank, MD oncodaily.com/insight/ptcog-… #OncoDaily #Oncology #Cancer #Health #Medicine #MedX #MedEd #MedNews CancerWorld

Better toxicity and better quality of life while keeping the similar survival (?)

So glad to meet the particle therapy global experts The Particle Therapy Co-Operative Group (PTCOG) in Argentina.

SACRAL CHORDOMA: Particle RT vs. Surgery Prospective SACRO Study Presented by Dr. Fossati No significant differences in PFS, OS, or local/distant failure. Although patients receiving RT had worse tumor locations, they showed numerically better outcome and lower toxicity.

Why Particle TX? Why Flash RT? We must continue exploring novel technologies to overcome current TX obstacles. Yesterday’s “experimental treatment” has become today’s “standard of care” such as IMRT, SBRT, and IO …… Aim to create better, cheaper and faster RT for future.