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Excited to kick-off studies with NASA and @thewooj to build Next-Generation human brain models to longitudinally track how diverse human brain are impacted by neurotoxic stress science.nasa.gov/biological-phy…

Thanks to Sergiu P. Pasca, @Mad_Lancaster, Giorgia Quadrato, Ben Novitch, Joel W. Blanchard, & Insoo Hyun for chatting with me, and @tvjrennie for first-rate edits and guidance. Read the fully story here: quantamagazine.org/lab-grown-huma…

Tissue chips mimic the function of human organs and are used to study diseases, test medications, & investigate cellular responses to spaceflight stressors. These small devices could help us take the next giant leap while benefiting human health on Earth: go.nasa.gov/3CSgfsI

About 1 in 5 of us have an APOE4 gene variant, the #1 genetic risk factor for Alzheimer's disease. But the mechanism for brain injury was a mystery, now getting unraveled (cholesterol processing by oligodendrocytes) nature.com/articles/s4158… @nature nature.com/articles/d4158…

Delighted by the fantastic presentation by @narayan_pri at CSHL on APOE biology. Fundamental biology with lots of future potential for major insights into this enigmatic protein. She is hiring so I encourage any interested trainees to consider her lab at the NIH!

Transcriptomic resource of 380 postmortem samples from multiple spinal cord segments from 154 individuals with #ALS implicates glial activation and suggests new risk genes New from Jack Humphrey, Towfique Raj and colleagues nature.com/articles/s4159…

Excited to Team up with BIAA to build more physiological models of human traumatic brain injury using patient stem cells Brain Injury Assoc. Friedman Brain Institute Mount Sinai Stem Cell

Congratulations Zhenyu Yue & the entire team, Bin Zhang, @JohnCraryMDPHD, Nan Yang, Zhuhao Wu and Joel W. Blanchard. What a great achievement! Thank you Parkinson's Foundation for the great work you do.

Mix together stem cell-derived neurons 💚, vascular ❤️& other brain cells 💙, allow them to self-assemble into droplet size 3D human brain 👉 WHAAAAT?! Louise Louro’s BEAUTIFUL IMAGE “The Brain Donut” is EXTRAORDINARY SCIENCE! VOTE #ArtoftheBrain #CallforImages #20 Most🧡s wins!

Congrats Stephen!!!

Congrats Louise!!!

Introducing the official Bond Lab website: thebondlab.com Interested in neural stem cell biology and a supportive training environment? The lab opens May 1 - come join us in NYC! Icahn School of Medicine at Mount Sinai Mount Sinai Stem Cell Friedman Brain Institute New PI Slack

Myelin dysfunction drives amyloid-β deposition in models of Alzheimer’s disease | oligodendrocytes 🤩 nature.com/articles/s4158…

Multiple positions open to join our ⁦CZI Science⁩ funded project—iPSC modeling, comp bio for multiomics from brain and blood, and a deep dive into immuno-vascular interactions as drug targets. DM if interested our team! #cureCADASIL #vcid# #endalz

Announcing the 13 winners of the 2024 New Investigator Award Program! Thank you to the Alzheimer's Association for supporting the expansion of this program! #NIAfundedADRC Learn about the winners and their research: naccdata.org/nacc-productiv…

Huge congrats to Dr. Jessica Schwarz Jessica Schwarz in my lab for winning the New Investigator Award! Her work aims to find mechanisms of risk and resilience to Alzheimer’s using our engineered mini-human brains. Thanks Alzheimer's Association National Alzheimer's Coordinating Center (NACC) for supporting this exciting work

.@repmikelawler We must continue to prioritize the well-being of the nearly 7 million Americans living with Alzheimer’s, their caregivers, and the millions more who will be impacted by dementia! #ENDALZ

Exciting postdoc positions available! Join in applying iPSC-derived human brain tissue to dissect and therapeutically target the root causes of neurodegeneration. @sinaiBrain, Mount Sinai Stem Cell Competitive salary and Subsidized housing provided. Please retweet!