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Happy to share our latest preprint on Synaptotagmin13 regulating endocrine cell egression and islet morphogenesis. Great effort by Aimée Bastidas Ponce, Sophie Tritschler, Marta Tarquis-Medina, Heiko Lickert, Coskun Lipid Cellar @ ZML Dresden, Fabian Theis and others invovled. biorxiv.org/content/10.110…

New Article online now CellStemCell: Microvessels support engraftment and functionality of human islets and hESC-derived pancreatic progenitors in diabetes models zpr.io/uEE9AZ5bFpDD

Congratulations, Anna 🥳🍾🥂

Ma et al demonstrate that the bromodomain and extraterminal domain inhibitor I-BET151 can robustly promote the expansion of PDX1+NKX6.1+ pancreatic progenitors, which can efficiently differentiate into functional pancreatic β cells. science.org/doi/10.1126/sc…

Very excited to share our new pre-print performing single-cell multiomics to characterize human stem cell-derived islets. New and unexpected insights contained within! @WashUEndo WashU Biomedical Engineering WashU Center of Reg Med @WUSTLdbbs biorxiv.org/content/10.110…

tinyurl.com/22sw73sm Highly functional stem-cell derived islets benchmarked broadly against primary islets. An important resource for you all, I hope! Work enabled by our excellent environment MetaStem STEMM Research Program

Congrats, @ThorstenKalten1 🥳🥂

Optimization of vitrification approaches significantly improves pancreatic islet cryopreservation for banking and boosts #transplantation outcomes in #diabetes nature.com/articles/s4159…

Great review from Chirag Chirag Jain, Ansar Ansarullah and Sara Sára Bileková on beta cell targeting in Nature Metabolism today - congratulations 🎉🎊🍾

Nicely in sync with #EASD2022, our new protocol paper for making stem cell-derived islets is now out in the wild! (Revealing all the tips and tricks!). Represents a huge historical effort from everyone in OtonkoskiLab. sciencedirect.com/science/articl…

I don’t think there is a more beautiful place to discuss #stemcell science than Hydra. Thank you StemCell Summer School for making this inspiring summer school possible this year 👏👏 I learned a lot from amazing faculty and delegates 🤩

Sexism in academia is bad for science and a waste of public funding. nature.com/articles/s4157…

Extremely happy to have reached this milestone 🥳🥂 Thank you to everyone who supported me along the way!

New Approach for Diabetes Therapies: Inceptor Regulates Insulin Homeostasis 👉t1p.de/i4a7a Scientists led by Prof. Heiko Lickert at #HelmholtzMunich have uncovered a new role for #Inceptor, a receptor regulating #insulin homeostasis. 💡Blocking Inceptor could boost

Very excited to see my PhD research with the Heiko Lickert lab published today. Was a pleasure to tackle this project with you, Sára Bileková

One of the cool parts of biology is that, even if you think you understand something, you can always go deeper. Case in point: insulin. It's been studied for over a century, but a paper out today uncovers a major mechanism of how the body manages insulin recycling. Briefly,

RESEARCH | Johanna Siehler,Sára Bileková, Heiko Lickert et al. (Helmholtz Munich | @HelmholtzMunich): Inceptor (insulin inhibitory receptor) regulates #insulin stores by directing proinsulin and insulin towards lysosomal degradation. nature.com/articles/s4225…