John LaMattina (@john_lamattina) 's Twitter Profile
John LaMattina

@john_lamattina

Dr. John LaMattina, senior partner PureTech Health, author & former president of Pfizer Global R&D.

ID: 295221061

linkhttps://www.johnlamattina.com calendar_today08-05-2011 16:08:04

5,5K Tweet

11,11K Followers

1,1K Following

Tara Bannow (@tarabannow) 's Twitter Profile Photo

So, so thrilled that our small but mighty team at STAT has won its first National Magazine Award for General Excellence. The judges cited 3 of STAT's series from last year, incl. Health Care's Colossus, our investigation into UnitedHealth Group. shorturl.at/g0x3O

Gunnar Esiason (@g17esiason) 's Twitter Profile Photo

Median age of survival for cystic fibrosis patients was 4-5 in 1954. I’m 34 in 2025. Today, some median project survival analyses say CF patients born today can expect to live to be 70+ Feels like we’re healthier now than ever before.

Median age of survival for cystic fibrosis patients was 4-5 in 1954. 

I’m 34 in 2025.

Today, some median project survival analyses say CF patients born today can expect to live to be 70+

Feels like we’re healthier now than ever before.
John LaMattina (@john_lamattina) 's Twitter Profile Photo

Verve gene-editing therapy lowers cholesterol without serious side effects in early study statnews.com/2025/04/14/ver… via STAT Congratulations Verve.

VitalTransformation (@vitaltransform) 's Twitter Profile Photo

📢 New VT Research! The IRA is driving a 68% aggregate drop in early-stage funding for small molecule drugs, with early-stage clinical trials also in decline. Our latest report shows how this puts future treatments for seniors at risk. Read more: buff.ly/pkV8vHB #IRA

📢 New VT Research!

The IRA is driving a 68% aggregate drop in early-stage funding for small molecule drugs, with early-stage clinical trials also in decline. Our latest report shows how this puts future treatments for seniors at risk. 

Read more: buff.ly/pkV8vHB

#IRA
VitalTransformation (@vitaltransform) 's Twitter Profile Photo

Why has early-stage funding for small molecule drugs dropped 68%, from $2B to $640M? The IRA’s 9-year price-setting window shortens their return period, increasing risk and driving early-stage capital elsewhere. Read our latest findings: buff.ly/pkV8vHB We Work For Health

Why has early-stage funding for small molecule drugs dropped 68%, from $2B to $640M? The IRA’s 9-year price-setting window shortens their return period, increasing risk and driving early-stage capital elsewhere.

Read our latest findings: buff.ly/pkV8vHB

<a href="/weworkforhealth/">We Work For Health</a>
John LaMattina (@john_lamattina) 's Twitter Profile Photo

My worry is that they will change it to 9 years for both small molecules and biologicals. Thus, the penalty will be even worse.

Ligand (@ligand_lgnd) 's Twitter Profile Photo

Ligand subsidiary Pelthos Therapeutics to merge with Channel Therapeutics Corp. The transaction will raise $50 million in equity capital, and the combined company will focus on commercializing ZELSUVMI™ for molluscum. Ligand is entitled to a 13% royalty on worldwide sales. bit.ly/4cAe11r

Ligand subsidiary <a href="/PelthosT/">Pelthos Therapeutics</a> to merge with <a href="/ChromocellThera/">Channel Therapeutics Corp</a>. The transaction will raise $50 million in equity capital, and the combined company will focus on commercializing ZELSUVMI™ for molluscum. Ligand is entitled to a 13% royalty on worldwide sales. bit.ly/4cAe11r
VitalTransformation (@vitaltransform) 's Twitter Profile Photo

The IRA sets Medicare’s maximum fair price at year 9 for small molecule drugs, 4 years sooner than for biologics. Since then, early-stage small molecule funding has dropped. Expect fewer new treatments for seniors by 2030. Read more: buff.ly/pkV8vHB We Work For Health

The IRA sets Medicare’s maximum fair price at year 9 for small molecule drugs, 4 years sooner than for biologics. 

Since then, early-stage small molecule funding has dropped. Expect fewer new treatments for seniors by 2030. Read more: buff.ly/pkV8vHB

<a href="/weworkforhealth/">We Work For Health</a>
VitalTransformation (@vitaltransform) 's Twitter Profile Photo

Claims that the IRA wouldn’t affect innovation overlooked how early-stage investors really make decisions. Our research shows the pipeline for senior-focused therapies is already narrowing. Read the full breakdown: buff.ly/Agz6GuJ We Work For Health #IRA #DrugPricing

John LaMattina (@john_lamattina) 's Twitter Profile Photo

Removal of the Pharma Advisory Committee rep is an issue. This is a nonvoting member not connected to the sponsor and an expert in the field. Plus PDUFA ensures such representation. Removal perpetrates the view of “evil Pharma”.

PureTech (@puretechh) 's Twitter Profile Photo

We’re proud to share new research in BMC Pulmonary Medicine (BMC) that captures the real-world experiences of people living with #idiopathicpulmonaryfibrosis. Conducted with #IPF experts & @PFForg, it highlights gaps in diagnosis, treatment options, and quality of

PureTech (@puretechh) 's Twitter Profile Photo

Just presented at #ATS2025: New preliminary 52-week open-label extension data from our Phase 2b ELEVATE #IPF trial reinforce deupirfenidone’s strong and durable efficacy — slowing lung function decline to the range expected in healthy older adults, with favorable tolerability.

Forbes (@forbes) 's Twitter Profile Photo

Meet India’s Self-Made Biologics Brewmaster Billionaire on.forbes.com/6014NL2lG (Photo: Guerin Blask For Forbes)

Meet India’s Self-Made Biologics Brewmaster Billionaire
on.forbes.com/6014NL2lG (Photo: Guerin Blask For Forbes)
OncoDaily (@oncodaily) 's Twitter Profile Photo

Paolo Tarantino Honored to Receive the 2025 Yvonne 'Top Voice' Award Presented by OncoDaily Paolo Tarantino Luiza Pamela Beato G Curigliano MD PhD oncodaily.com/positive/yvonn… #Cancer #Oncology #OncoDaily #Health #ASCO25 #ASCO #Medicine CancerWorld

Paolo Tarantino Honored to Receive the 2025 Yvonne 'Top Voice' Award Presented by OncoDaily

<a href="/PTarantinoMD/">Paolo Tarantino</a> <a href="/luiza_beato/">Luiza Pamela Beato</a> <a href="/curijoey/">G Curigliano MD PhD</a> 

oncodaily.com/positive/yvonn…

#Cancer #Oncology #OncoDaily #Health #ASCO25 #ASCO #Medicine <a href="/CancerWorldmag/">CancerWorld</a>
Medscape (@medscape) 's Twitter Profile Photo

A molecular variant of an older, hard-to-tolerate antifibrotic agent showed promise for reducing decline in forced vital capacity (FVC) over 26 weeks among patients with idiopathic pulmonary fibrosis (IPF). ms.spr.ly/6016SiGCs

A molecular variant of an older, hard-to-tolerate antifibrotic agent showed promise for reducing decline in forced vital capacity (FVC) over 26 weeks among patients with idiopathic pulmonary fibrosis (IPF). ms.spr.ly/6016SiGCs
Matthew Herper (@matthewherper) 's Twitter Profile Photo

There are a LOT of problems with the FDA Commissioner's National Priority Vouchers. First that they're given out by the commissioner. But also: faster drug approvals are good, but these would be faster than any drug approvals ever. Big promises like this should be approached

VitalTransformation (@vitaltransform) 's Twitter Profile Photo

In an ever-evolving healthcare landscape, understanding how policy shapes innovation becomes increasingly important. Without that understanding - barriers to drug development, such as uneven exclusivity periods, can halt the development of new treatments. We sat down for a

In an ever-evolving healthcare landscape, understanding how policy shapes innovation becomes increasingly important. Without that understanding - barriers to drug development, such as uneven exclusivity periods, can halt the development of new treatments.

We sat down for a