Excited to share our latest collaboration with the @corrylab and Zhang Lab, this time on OSCA/TMEM63 channels out today in nature Victor Chang Cardiac Research Institute nature.com/articles/s4158…

First structures that illustrate opening of wild-type human TRPV3 (no sensitizing mutations!) by agonists, 2-APB or THCV, acting through different binding sites and expelling lipid from the vanilloid site. Kirill Nadezhdin @arthurCantab Ira Talyzina science.org/doi/10.1126/sc…

A pervasive view is that TRP channels represent primary sensors of mechanical forces. Along with @PooleLab1 and Boris Martinac we reviewed the evidence supporting this in Trends in Biochemical Sciences cell.com/trends/biochem…

Baron Chanda Jonathan Mount Yuan Lab A huge shoutout to my 'partner in crime' Jonathan Mount and the invaluable contributions of Jian Huang, john cowgill, Yongchang Chang, Kathleen Bickel, the Yuan Lab, and the Jianhan Chen lab at UMass. I’ve learned a lot from these amazing people!

The open state was certainly tricky to capture and revealed more than a few unexpected features! Happy to have played a role. Thanks and congratulations to Verena Burtscher Baron Chanda Yuan Lab john cowgill, Yongchang Chang, Jianhan Chen and Jian Huang, and Kathleen Bickel

Any sufficiently advanced research project is indistinguishable from a drunken walk.

Congratulations to Drs. Irfan Lodhi, Jeffrey Millman, Maria Remedi, and Julie Silverstein on achieving full professorship in their careers! Learn about each of their journeys: bit.ly/3Xs4FyM. Jeffrey Millman Irfan Lodhi @WUDeptMedicine

Nature research paper: Signatures of magnetism control by flow of angular momentum go.nature.com/4e9sFfz

Conformational change in transitioning from the inactive UvrD1 monomer-DNA structure to the leading subunit of the activated UvrD1 dimer-DNA structure. biorxiv.org/cgi/content/sh…

My PI: So, do you have a plan? Me: I have concepts of a plan My PI:

Excellent thesis defense by Dr. Gao! Congratulations Jian, we are very proud of you! 🥳

Wonderful news! Parafilm M rules! Very well-deserved recognition after helping so many other #NobelPrize winners achieve their breakthroughs! Congratulations Moved on to @parafilmm.bsky.social

Collaborative work of slavica pavlovic djuranovic, Yaser Hashem, Jovanovic Lab and Sergej Djuranovic - a new method to isolate ribosomes and translational material in minutes. We show multiple usage of our RAPPL method in biochemical and structural assays with ribosomes. Please be free to contact

If Billionaires like Jeff Bezos and Elon Musk don't want Kamala Harris to win, maybe she's actually good for people who aren't billionaires.

This meme is a joke but also life-changing advice if taken to heart

Happy Halloween!

Two of the most qualified women in the country ran for president against an unqualified, racist game show host who had a history of committing fraud and sexual abuse. And the country was basically split 50-50. That should tell us some things.

Dear Ion Channel and Structural Biology friends - I'm moving over to Bluesky! I'll still be here from time to time but plan to be more active over there ([email protected]). Catch you on the flipside!

Oh please. There’s a lot of room for improvement at the NIH, but its entire budget is less than 1% of total federal expenditures in 2024.

Fixed it: --> last year, the U.S. sold more educational services to the rest of the world than it sold in natural gas and coal **combined** --> every $1 of research funded by NIH generates $2.56 in economic activity --> more than 1.1M foreign students come to the U.S. each year