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Happy to share our latest work with Jong-Woo Sohn in Journal of Experimental Medicine (rupress.org/jem/article/21…), where we present experimental evidence linking deficits in hypothalamic Mc4r to antipsychotic drug-induced weight gain. UTSW Media Relations UT Southwestern O'Donnell Brain Institute UTSW Internal Medicine UTSW Neuroscience UTSW Science 1/

Li, Jong-Woo Sohn, Chen Liu et al. UT Southwestern O'Donnell Brain Institute develop a new mouse model that recapitulates risperidone-induced metabolic syndrome, revealing that this atypical antipsychotic drug causes weight gain via hypothalamic melanocortin 4 receptors bit.ly/3ocFbSU #Neuroscience

In Journal of Experimental Medicine, Li, Jong-Woo Sohn, Chen Liu et al. UT Southwestern O'Donnell Brain Institute develop a new mouse model that recapitulates risperidone-induced metabolic syndrome, revealing that this atypical antipsychotic drug causes weight gain via hypothalamic melanocortin 4 receptors bit.ly/3ocFbSU

New findings identify molecular mechanism behind rapid weight gain in patients treated with risperidone. bit.ly/2ReHtVl

An interdisciplinary team at KAIST has revealed a mechanism underlying most common cause of #epilepticseizures 🧐🔬 🔗news.kaist.ac.kr/newsen/html/ne…

Want to present your research project related to #neuroendocrinology to an international conference? Submit an abstract to one of the scientific sessions of #ICN2022 to be held in #Glasgow on August 7-10, 2022 icn2022.org BSN sneuroendo

Li Li, Chen Liu, Jong-Woo Sohn et al. reveal that the atypical antipsychotic risperidone targets hypothalamic melanocortin 4 receptors to cause weight gain. bit.ly/2YbGwAz From our #Neuroscience Collection to accompany #SfN21 👉 bit.ly/2ZOlZlW

Happy to share our latest work with Jong-Woo Sohn in Cell Reports (cell.com/cell-reports/f…), where we identify Gαi/o-coupled serotonin (5-HT) 2C receptors (Htr2c) and determine their roles in feeding regulation. KAISTPR UT Southwestern O'Donnell Brain Institute UTSW Media Relations UTSW Neuroscience UTSW Science 1/

Happy to share our latest work with Jong-Woo Sohn in Journal of Experimental Medicine rupress.org/jem/article/21… where we report the appetite-suppressing effect of commonly used antimigraine drugs and illustrate the underlying neural circuit in mice. UT Southwestern O'Donnell Brain Institute UTSW Internal Medicine UTSW Neuroscience UTSW Science 1/

.@christ_lili Jong-Woo Sohn Chen Liu et al report the appetite-suppressing effect of a class of commonly prescribed antimigraine drugs in mice & illustrate the underlying neural pathway using a combination of genetic, metabolic, & transcriptomic analyses bit.ly/3uwzCCR

Common migraine meds, triptans, could also treat obesity, says Chen Liu of UTSW Media Relations in a new Journal of Experimental Medicine paper. Obese mice taking triptans ate less, lost weight, improved glucose over 1 month. The effect was mediated by the Htr1b serotonin receptor. utsouthwestern.edu/newsroom/artic…

I am glad to share the latest work from my lab on the role of TRPV1 channel in the regulation of sympathetic activity and blood pressure by MC4R. Melanocortin-4 receptors activate sympathetic preganglionic neurons and elevate blood pressure via TRPV1 cell.com/cell-reports/f…

Melanocortin-4 receptors activate sympathetic preganglionic neurons and elevate blood pressure via TRPV1 dlvr.it/Sc8sTb

.@christ_lili Jong-Woo Sohn Chen Liu et al report the appetite-suppressing effect of a class of commonly prescribed antimigraine drugs in mice & illustrate the underlying neural pathway bit.ly/3uwzCCR From our #Neuroscience Collection: bit.ly/3Efip6b #SfN22

“…you have to relish the rejection. Rejection is the evidence of your hustle. Rejection is the sign that you are throwing yourself against the door.” theatlantic.com/culture/archiv…

Protocol to prepare mouse spinal cord for patch-clamp and histology experiments star-protocols.cell.com/protocols/2732

We are excited to announce the winners of the 2024 Laureate Awards, which recognize the highest achievements in the #endocrinology field. They will be honored at #ENDO2024 next June in Boston, MA. Learn more: bit.ly/3OGwaiw

Subset of neurons in #hypothalamus increases appetite & decreases #thermogenesis. Jong-Woo Sohn &co show that ion channel GIRK2 functions in hypothalamic NPY/AgRP neurons to increase energy expenditure in mice and may control body weight KAISTPR #PLOSBiology plos.io/3qGa8Ev

I am excited to share our new paper just published in PLOS Biology, which identifies a new role for GIRK2 in the AgRP neurons. I thank @KWickMN and twitterless Prof. Seyun Kim for their generous support. journals.plos.org/plosbiology/ar…

NEW SPECIAL ISSUE from the JNE featuring articles from the International Congress of Neuroendocrinology 2022 #ICN2022 held in Glasgow, UK All articles either open access or free for 2 months Browse: onlinelibrary.wiley.com/toc/13652826/2… BSN