Jonathan Martinez Fabregas (@jonmarfab) 's Twitter Profile
Jonathan Martinez Fabregas

@jonmarfab

Ollie's dad. Cell biologist. EMERGIA-funded independent researcher. Ramon y Cajal & MSCA alumni. Lysosomal biology in cancer and immune system.

ID: 1492928768637288453

linkhttps://www.cabimer.es/en/jonathan-martinez-fabregas/ calendar_today13-02-2022 18:29:03

29 Tweet

62 Followers

118 Following

FEBS Open Bio (@febsopenbio) 's Twitter Profile Photo

🔎Lysosomal peptidases—intriguing roles in cancer progression and neurodegeneration 🩺Do they have potential in the diagnosis and treatment of patients? 🔗buff.ly/3JDMdsX univerzalj Jožef Stefan Institute #Lysosomal #Peptidases #Neurodegeneration #CancerBiology

🔎Lysosomal peptidases—intriguing roles in cancer progression and neurodegeneration

🩺Do they have potential in the diagnosis and treatment of patients?

🔗buff.ly/3JDMdsX

<a href="/unilj/">univerzalj</a> <a href="/JSI_SLO/">Jožef Stefan Institute</a>

#Lysosomal #Peptidases #Neurodegeneration #CancerBiology
FEBS Open Bio (@febsopenbio) 's Twitter Profile Photo

🆕Here Jonathan Martinez Fabregas Joaquín Tamargo Azpilicueta Irene Diaz Moreno unwind the complex signaling pathways that lysosomal hydrolases function in 🫧How are lysosomal proteases secreted in a controlled fashion and which processes do they control upon release? 🔗buff.ly/3MQ1vxB #CellMetabolism

🆕Here <a href="/Jonmarfab/">Jonathan Martinez Fabregas</a> <a href="/TamargoJoaquin/">Joaquín Tamargo Azpilicueta</a> <a href="/idiazmoreno/">Irene Diaz Moreno</a> unwind the complex signaling pathways that lysosomal hydrolases function in

🫧How are lysosomal proteases secreted in a controlled fashion and which processes do they control upon release?

🔗buff.ly/3MQ1vxB

#CellMetabolism
FEBS Open Bio (@febsopenbio) 's Twitter Profile Photo

🆕Review on mTOR–lysosome & ageing This review examines the bidirectional relationship between mTORC1 & the #lysosome and how #mTORC1 inhibition + activation of the #autophagy–lysosome pathway can slow the molecular hallmarks of #ageing 🔓buff.ly/3juXTUd Dr Célia Fourrier

🆕Review on mTOR–lysosome &amp; ageing

This review examines the bidirectional relationship between mTORC1 &amp; the #lysosome and how #mTORC1 inhibition + activation of the #autophagy–lysosome pathway can slow the molecular hallmarks of #ageing

🔓buff.ly/3juXTUd <a href="/Celia_Fourrier/">Dr Célia Fourrier</a>
Moraga Lab (@labmoraga) 's Twitter Profile Photo

Really happy to see this one out Science Immunology (science.org/doi/10.1126/sc…). Full collaboration with Roychoudhuri Lab Suman MITRA. We hijack the acidic tumor microenvironment to engineer pH-selective IL-2 variants eliciting potent anti-tumor responses without toxicity. 1/2

Cell Signal and Immunology, University of Dundee (@uodcellsigimm) 's Twitter Profile Photo

!! Delighted to shout about Moraga Lab and their latest work with Suman MITRA published Science Immunology !! IL-2 is inactivated by the acidic pH environment of tumors enabling engineering of a pH-selective mutein. (AND featured as the cover no less!). science.org/doi/10.1126/sc…

!! Delighted to shout about <a href="/LabMoraga/">Moraga Lab</a> and their latest work with <a href="/at_Mitralab/">Suman MITRA</a> published <a href="/SciImmunology/">Science Immunology</a> !! 

IL-2 is inactivated by the acidic pH environment of tumors enabling engineering of a pH-selective mutein. 

(AND featured as the cover no less!). 

science.org/doi/10.1126/sc…
Jonathan Martinez Fabregas (@jonmarfab) 's Twitter Profile Photo

Estimado Domènec Espriu según mi evaluación R3 ser RyC, PI responsable de proyecto EMERGIA competitivo (140k) financiado Junta de Andalucía , codireccion de TFMs y TFGs (UK y ES), autor de correspondencia y miembro de comité editorial no muestra independencia-liderazgo?

Catalina García (@linagarcia_and) 's Twitter Profile Photo

La atención paliativa de personas con enfermedades avanzadas o terminales es uno de los retos fundamentales de los sistemas de salud. Hoy es el Día Mundial de los #CuidadosPaliativos y participo en la caminata que han organizado en #Úbeda.

La atención paliativa de personas con enfermedades avanzadas o terminales es uno de los retos fundamentales de los sistemas de salud.

Hoy es el Día Mundial de los #CuidadosPaliativos y participo en la caminata que han organizado en #Úbeda.
Jonathan Martinez Fabregas (@jonmarfab) 's Twitter Profile Photo

If you want to know more about our work Cabimer unraveling the link between the extralysosomal activity of lysosomal proteases and cancer drop by poster P25 at #ASEICACongress

If you want to know more about our work <a href="/cabimer/">Cabimer</a> unraveling the link between the extralysosomal activity of lysosomal proteases and cancer drop by poster P25 at #ASEICACongress
Hugh Kearns (@ithinkwellhugh) 's Twitter Profile Photo

For Christmas I want a dragon. Be realistic. OK. I want my paper to be accepted without revisions. What colour do you want your dragon?

For Christmas I want a dragon.
Be realistic.
OK. I want my paper to be accepted without revisions.
What colour do you want your dragon?
Jonathan Martinez Fabregas (@jonmarfab) 's Twitter Profile Photo

Interesad@ en una #PhDposition? Disponible contrato de 3 años para estudiar la conexión entre las funciones nucleares de las proteasas lisosomales y el cáncer mediante aproximaciones multi-omicas en @CABIMER. Interesad@ -> contacta por email. Please RT!

Interesad@ en una #PhDposition? Disponible contrato de 3 años para estudiar la conexión entre las funciones nucleares de las proteasas lisosomales y el cáncer mediante aproximaciones multi-omicas en @CABIMER. Interesad@ -&gt; contacta por email. Please RT!
Moraga Lab (@labmoraga) 's Twitter Profile Photo

Excited to share our newest full collaboration with Bubeck Lab. We provide structural insights that help explain how mutations in gp130 that do not disrupt cytokine binding cause signaling defects and immunodeficiencies in humans. doi.org/10.1038/s41467…, Cell Signal and Immunology, University of Dundee

Psancholab (@psancholab) 's Twitter Profile Photo

Abrimos nuevos grupos de peer mentoring al nivel de IPs junior y emergentes!! Mi experiencia en este tipo de mentoring no puede ser más positiva, lo recomiendo 💯

Laura_Corrales (@laura_corralesg) 's Twitter Profile Photo

We have a PhD student position available dealing with the generation of synthetic enzymatic organelles in cyanobacteria. Come join a #newPI at IBVF @investigaUS

We have a PhD student position available dealing with the generation of synthetic enzymatic organelles in cyanobacteria. Come join a #newPI at <a href="/IBVF_Sevilla/">IBVF</a> @investigaUS
Journal of Experimental & Clinical Cancer Research (@journalofexper1) 's Twitter Profile Photo

Just published!✅ #Radiotherapyresistance driven by #Asparagineendopeptidase through ATR pathway modulation in #breastcancer Check it out😃 jeccr.biomedcentral.com/articles/10.11… #Genomicstability #DNAdamage

Just published!✅

#Radiotherapyresistance driven by #Asparagineendopeptidase through ATR pathway modulation in #breastcancer

Check it out😃
jeccr.biomedcentral.com/articles/10.11…

#Genomicstability
#DNAdamage