🔥The 9th Round of Easy Loan, Earn $40 Reward is in progress❗️ ⏰ Promotion Period: January 15th - Feburary 15th, 2025 👉 Register now and check more details at gate.io/campaigns/358

Just Published!🔥 #𝐂𝐚𝐧𝐜𝐞𝐫𝐚𝐬𝐬𝐨𝐜𝐢𝐚𝐭𝐞𝐝𝐟𝐢𝐛𝐫𝐨𝐛𝐥𝐚𝐬𝐭𝐬 𝐚𝐬 𝐚 𝐩𝐨𝐭𝐞𝐧𝐭𝐢𝐚𝐥 𝐧𝐨𝐯𝐞𝐥 #𝐥𝐢𝐪𝐮𝐢𝐝𝐛𝐢𝐨𝐩𝐬𝐲 𝐦𝐚𝐫𝐤𝐞𝐫 𝐢𝐧 𝐜𝐚𝐧𝐜𝐞𝐫 𝐩𝐚𝐭𝐢𝐞𝐧𝐭𝐬 Enjoy your reading🍷 jeccr.biomedcentral.com/articles/10.11… #Bloodbasedbiomarkers #Circulatingtumorcells

Online!🐞 Reprogramming the #breasttumor immune microenvironment: cold-to-hot transition for enhanced #immunotherapy Full text⏬ jeccr.biomedcentral.com/articles/10.11… #ColdTumor #HotTumor #Cancervaccine #Immunecheckpoint

New Review!🍩 Targeting #glutamine metabolism as a potential target for cancer treatment Look here👇 jeccr.biomedcentral.com/articles/10.11… #MetabolicReprogramming #ImmuneEvasion #DrugResistance

Online!📲 Immune checkpoint inhibition perturbs neuro-immune homeostasis and impairs #cognitivefunction Full text👇 jeccr.biomedcentral.com/articles/10.11… #Immunotherapy #Melanoma #Murinemodel #Neuroinflammation

New study!🌈 Inhibition of #autophagy enhances the antitumor efficacy of T/CAR T cell against #neuroblastoma Learn more here👇 jeccr.biomedcentral.com/articles/10.11… #Immunotherapy #PediatricTumor #Immunecells #Chloroquine

New Review!🧩 Precision immune regulation in KRAS-mutated cancers: the final piece of the puzzle? Look here👇 jeccr.biomedcentral.com/articles/10.11… #KRASmutation #Immunotherapy #TumorMicroenvironment

Online!🍀 Amino acid transporter #LAT1 (SLC7A5) promotes #metabolicrewiring in TNBC progression through the L-Trp/QPRT/NAD+ pathway Full paper⏬ jeccr.biomedcentral.com/articles/10.11… #TripleNegativeBreastCancer #Glycolysis #Metabolism

New study!🍟 #Adipocytes-induced ANGPTL4/KLF4 axis drives #glycolysis and #metastasis in #triplenegativebreastcancer For free💻 jeccr.biomedcentral.com/articles/10.11…

New!🥳 Genomic profiling of a collection of patient-derived xenografts and cell lines identified #ixabepilone as an active drug against chemo-resistant #osteosarcoma Read here👇 jeccr.biomedcentral.com/articles/10.11… #PatientDerivedXenografts #DrugResistance

Online!🦠 PHGDH drives 5-FU #chemoresistance in #colorectalcancer through the #Hedgehogsignaling Look here👇 jeccr.biomedcentral.com/articles/10.11… #Serine #Stemness

New study!📲 PARP9-PARP13-PARP14 axis tunes #colorectalcancer response to #radiotherapy Full text👇 jeccr.biomedcentral.com/articles/10.11… #3Dcellculture #PARPgeneExpression

Happy 60th birthday to Dr. Giovanni Blandino 🎂 🔬Head of the Translational Oncology Research Unit 🤵Scientific Director ff 💻JECCR Deputy Editor at Regina Elena National Cancer Institute (Rome) Our best wishes for this special day! 🍾

New!🧪 WDR3 undergoes phase separation to mediate the therapeutic mechanism of #Nilotinib against #osteosarcoma Look here👇 jeccr.biomedcentral.com/articles/10.11… #IDRmutation #LiquidLiquidPhaseSeparation

Online!🩸 In-depth assessment of BRAF, NRAS, KRAS, EGFR, and PIK3CA mutations on cell-free DNA in the blood of #melanoma patients receiving immune checkpoint inhibition Full text⬇️ jeccr.biomedcentral.com/articles/10.11… #CirculatingTumorDNA #LiquidBiopsy

New Review!📢 Balancing between #cuproplasia and #copper-dependent cell death: molecular basis and clinical implications of #ATOX1 in cancer Check it out👇 jeccr.biomedcentral.com/articles/10.11… #Copperhomeostasis #Cuproptosis #OxidativeStress

New study!📲 Unraveling resistance mechanisms to the novel nucleoside analog RX-3117 in #lungcancer: insights into #DNArepair, cell cycle dysregulation and targeting PKMYT1 for improved therapy Learn more📚 jeccr.biomedcentral.com/articles/10.11… #NucleosideAnalogs #Chemoresistance

Online!😃 m5C-modified circRREB1 promotes #lungcancer progression by inducing #mitophagy For free🪁 jeccr.biomedcentral.com/articles/10.11… #circularRNAs #RNAmodification

📌Comparing Xenium 5K and Visium HD data from identical tissue slide at a pathological perspective Read here the full Commentary🔬 jeccr.biomedcentral.com/articles/10.11… #SpatialTranscriptomics #LungAdenocarcinoma

New!🧠 Targeting #autophagy and plasminogen activator inhibitor-1 increases survival and remodels the #tumormicroenvironment in #glioblastoma Full paper👇 jeccr.biomedcentral.com/articles/10.11… #MurineModel #Glioma #Lucanthone

Online!🍹 Integrated multi-omics profiling reveals the role of the #DNAmethylation landscape in shaping biological heterogeneity and clinical behaviour of #metastaticmelanoma Look here💡 jeccr.biomedcentral.com/articles/10.11… #ImmuneCheckpointBlockade #DNMTinhibitor