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"We fail much more than we ever succeed. We know that. We accept that. We're amazing at dealing with failure. That's what scientists do." - chemist David MacMillan (David MacMillan) on failure at the #NobelPrizeDialogue in Brazil. Watch the full dialogue: bit.ly/3UNzDPa

“It is not true that people stop pursuing dreams because they grow old, they grow old because they stop pursuing dreams.” #OTD in 1967 Gabriel García Márquez's masterpiece of magical realism, 'One Hundred Years of Solitude', was published. Read more: bit.ly/2MWeIFm

👇🏾Excellent tweetorial by lead author Ben Omega Petrazzini on our study on rare variant association analyses with a machine learning-based marker for coronary artery disease Nature Genetics. nature.com/articles/s4158…

"I refuse to accept the view that mankind is so tragically bound to the starless midnight of racism and war." Watch Martin Luther King Jr.'s Nobel Peace Prize speech, where he accepted the award on behalf of the American civil rights movement: bit.ly/3bJCQuc

web.stanford.edu/group/pritchar… Catching up with the April 2024 updates on population structure from Jonathan Pritchard Stanford University, the scientist who developed some of these key concepts. Chapter 3.1 ends with some must-read references from US Census & NAM population descriptors. #Genetics

June is for graduations, summer interns, welcoming new colleagues & class photos. Thanks Jiayu (our style guru) for the photo. #IBD Celebrating #science

Happy Juneteenth. A moment to pause, give thanks & contemplate freedom. #FDR's 4 freedoms == 1) freedom of speech 2) freedom of worship 3) freedom from want 4) freedom from fear. Key--remember today how recent Juneteenth's freedom was. Southview from 4 Freedoms Park breathtaking

doi.org/10.1038/s41587… Nature Biotechnology Important benchmarking, code and #data from #PBMCs, across platforms. 10x Genomics does well Reassuringly consistent cell estimates of DARs (differentially accessible regions)

This resonates with me--still with low grade coughing > 3 weeks after acute Covid infection (with early Paxlovid Rx). New Covid exposure == systemic, acute infection + trigger for chronic cough (back running again, at least)

Who is your idol? Hear medicine laureate Katalin Karikó speak about her idols – teachers. Listen to the full conversation with Karikó that took place at our Nobel Prize Conversations event in Madrid: youtube.com/watch?v=PbRxGo…

A Buckeye for many years!! Ohio State

doi.org/10.1016/j.immu… Superb study from Carla Rothlin Yale University on IL4-mediated reduced immune response (& bystander effects) of naive T cells w/ active gut helminths. Clearing restores this. Implications for #IBD & rising incidence w/ helminth clearing. #Environment #guthealth

Improving the predictive power of mouse models go.nature.com/3yNEUze

Pre-meeting for the 5th CCAiD-@asanibd seminar. See you all on 13 Dec in Seoul! 김은수 Suk-Kyun Yang Byong Duk Ye Sung Wook Hwang MD 권은자

Article in The New York Times on drug price reductions. Why do #crohns disease and ulcerative colitis remain hidden? Stelara listed for “autoimmune conditions”. Jardiance listed as drug for specific disease, not “metabolic/heart/kidney conditions” Peter Loftus Uma Mahadevan #IBDSuperHeroes

Have you ever wished to view the world from a completely new perspective? This thread on cool maps is here to blow your mind. 1. The Mississippi River and its tributaries

A wonderful talk today by Lluis Quintana-Murci on the evolutionary genetic drivers of immune responses in diverse human populations. Thanks to Miriam Merad, MD, PhD for organizing.

Vasculature of adult zebrafish gills. Credit to Dr. Madina Wane. #ZebrafishZunday

What hope looks like. nytimes.com/2024/09/16/hea… Why we do #science #gene_therapy

Very grateful to Nature Aging for highlighting our work from the lab of Miriam Merad, MD, PhD on hematopoietic aging and its vital role in aging-driven tumor progression. Read the highlight: nature.com/articles/s4358… View our paper: science.org/doi/10.1126/sc…