Julienne L. Carstens
@julielcarstens
Dedicated wife and mother. Assistant Professor at UAB. Metastatic pancreatic cancer biologist.
ID: 1170841026954768384
08-09-2019 23:27:47
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255 Followers
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New cross species study examining #PancreaticCancer precursors in Journal of Clinical Investigation from Dr. Neeha Zaidi Won Jin Ho Dr. Elizabeth Jaffee Johns Hopkins Kimmel Cancer Center Spatial Proteomics and Transcriptomics Reveal Early Immune Cell Organization in Pancreatic Intraepithelial Neoplasia insight.jci.org/articles/view/…
Our spatial FFPE-ATAC-seq is now published in Nature Communications! With extensive optimizations, it performs well across diverse tissues, unlocking the vast FFPE archive for spatial epigenomics. Big congrats to Pengfei Guo Pengfei_Guo, Yufan Chen, and the team! nature.com/articles/s4146…
Great news from NIH! Thank you Jay Bhattacharya, MD, PhD for your leadership on this. The same will apply to FDA funded studies.
Proud to share Jose M. Adrover’s (new PI The Francis Crick Institute) paper: As a postdoc (Cold Spring Harbor Laboratory/Johns Hopkins Medicine), he found #NETs in necrotic tumors—I shrugged. But he looked closer: NETs block tumor vessel perfusion, causing necrosis, hypoxia, EMT & #Metastasis. nature.com/articles/s4158… @JHU_BDP nature
Just saw this preprint from Rosie Sears lab where CODA #AI is used for automated assignment & segmentation of histological lesions in murine pancreas. On behalf of graduate students & postdoc fellows in #PancreaticCancer research - Thank you Ashley Kiemen Laura DeLong Wood!
Been waiting for this elegant work from Christine Chio Herbert Irving Comprehensive Cancer Center! New preprint that identifies a novel iron-MSRA-PKA axis driving #PancreaticCancer cachexia. An Iron-regulated Signaling Pathway Controls Adipose Browning and Cancer Cachexia biorxiv.org/content/10.110…
🧵 Encouraging early results from Elicio Therapeutics KRAS-targeting vaccine in #pancreaticcancer and colorectal cancer published in Nature Medicine, feat. co-corresponding authors/PanCAN SMAB members Dr. Shubham Pant and Eileen M O’Reilly. nature.com/articles/s4159…
Terrific preprint by Hartland Jackson using imaging mass cytometry (IMC) & matched genomics for building multimodality prediction models: Integrated spatial proteomics of human PDAC uncovers an expanded tumour–immune– stroma spectrum with genomic associations biorxiv.org/content/10.110…
Small series but important data from Erika J. Crosby, PhD Duke University School of Medicine A platform for multisite immune profiling of premetastatic #PancreaticCancer at single-cell resolution link.springer.com/article/10.100… scRNA seq & TCR profiling of tumor free liver matched to PBMC & primary tumor.