Cubic cleared confetti embryonic heart. Imaged with lightsheet Microscopy Core at UCSD School of Medicine, processed with #Bigstitcher and visualized with ChimeraX (bsky: chimerax.ucsf.edu) #FluorescenceFriday

I had really cool editors who take active role in shaping/improving manuscripts. But today I had this; c'mon, as Britney sang you better work... #AcademicTwitter #academicintegrity

If it ain’t green and glow in the dark it ain’t science. Leftovers from #fluorescent protein #mClover3 purification. #AcademicTwitter

We are seeking candidates for a fully funded postdoctoral position (3 years) in the Shaner Lab at UCSD. The successful candidate will lead projects focused on genetically encoded biosensor design, validation, and optimization. adc-nice.org/postdoctoral-r…

Our paper on #ALPK3 is out in JAHA. We demonstrate that loss of ALPK3 and established factor for genetic cardiomyopathy leads to accumulation of thick filament components, possibly via MuRF- muscle specific E3 ubiquitin ligases. ahajournals.org/doi/10.1161/JA…

New study reveals ALPK3 is crucial for heart health! Mouse models show its key role in maintaining sarcomere structure. #AHAJournals Julius Bogomolovas UCSD Cardio-Labs ahajrnls.org/4j2KX50

our new paper in Communications Biology. We show that Tnnt2 intronic RNAscope probe reliably identifies cardiomyocytes —even through mitosis and nuclear envelope breakdown—overcoming the limitations of traditional CM identification methods. nature.com/articles/s4200…

UCSD Biosensor Core (ucsd-biosensor-core.vercel.app) is hiring a Research Associate: cell culture, lab maintenance, opportunities to assist with probe development, live cell imaging, and data analysis. Full time, pay range $26.52 - $31.64 / Hour. employment.ucsd.edu/biosensor-core…