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I would never work on lipids I said. Sugars are way cooler, I said...but here we go! Proud of this work on OMV lipids in Bacteroides by Mariana Sartorio and Ezequiel Valguarnera published in Microbiology Spectrum, open access journal from the ASM journals.asm.org/doi/10.1128/sp…

Happy to share our recent publication PLOS Biology. 'Dynamic proton-dependent motors power T9SS and gliding motility in Flavobacterium'. Congratulations Maxence Vincent, Doan Thierry and all coauthors ! journals.plos.org/plosbiology/ar…

Very excited to share that we published our new story "T6SS penetration into Gram+ cells" in the first issue of a new microbiology journal mLife. doi.org/10.1002/mlf2.1…

Our company is growing! Omniose (formerly VaxNewMo) started like a crazy idea with Christian Harding, a post doc in my lab, but now we are seriously developing new antibacterial vaccines. Exciting times coming! businesswire.com/news/home/2022…

Congrats Anna Hooppaw and the rest of the team. Phenylacetic(PAA) is a hormone in plants. We report that Acinetobacter adjusts PAA catabolism in response to antibiotic and oxidative stress. Levels of PAA appear to impact transcription of multiple genes. journals.asm.org/doi/10.1128/mb…

Very happy to present the cryo-tomography structure of the P. gingivalis Type IX secretion system (T9SS) - a collaborative work with Bo Hu and Rich Lamont. Labo d'Ingénierie des Systèmes Macromoléculaires @univamu @CNRS_INSB A unique secretion machinery with multiple secretion centers. pnas.org/eprint/X23X5UP…

Happy to share our most recent work. A link between transcription termination, H-NS gene-silencing and bistability in virulence gene expression of Salmonella . Big thanks to all my coworkers, it was a pleasure and a privilege to work with you! biorxiv.org/content/10.110…

Congrats Clay Jackson-Litteken and the rest of the team for discovering InvL, new type of invasin in Acinetobacter. InvL is secreted the T2SS and is required for A. baumannii uropathogenesis. journals.asm.org/doi/10.1128/mb…

What distinguishes A. baumannii from its less pathogenic next relatives? Happy to share the results of this collaboration led by the Ebersberger lab. Congrats to all the authors!journals.plos.org/plosgenetics/a…

Happy to share our new preprint reporting that the bacterial effector itself mediates target cell entry via its glycine zipper motif(s). Proud of 1st author, my Ph.D. student Jemal Ali Jemal Ali and thanks all authors contributing to this challenging work. biorxiv.org/content/10.110…

I am so excited to share our review of drug independence and its role in curative cancer combination therapy just published #OpenAccess in Trends in Cancer. cell.com/trends/cancer/… #MathOnc #CompMed #SysBio UNC Pharmacology Adam C Palmer UNC School of Medicine UNC-Chapel Hill UNC Lineberger (1/8)

Thanks to Nello, Pepe and all co-authors, great job everyone! Pervasive transcription enhances the accessibility of H-NS–silenced promoters and generates bistability in Salmonella virulence gene expression | Proceedings of the National Academy of Sciences pnas.org/doi/10.1073/pn…

New preprint online! My PhD student Neil Lorente Cobo's first manuscript. A great collaboration biochemically characterizing the Salmonella #T6SS effector Tlde1a with Ethel Bayer Santos and Waldemar Vollmer. ManitobaMicrobiology UManitoba Science MiSC U of M U of Manitoba MicroGSA biorxiv.org/content/10.110…

Ergosterol distribution controls surface structure formation and fungal pathogenicity biorxiv.org/cgi/content/sh… #biorxiv_micrbio

Happy to share these beautiful studies about ergosterol transport in C. neoformans, done by Keeley Choy with help from Ellie Gaylord. Two talented and insightful Wash U DBBS graduate students – it’s a privilege to work with them! @WUSM_MolMicro @WUSTLdbbs biorxiv.org/content/10.110…

I am still looking for postdocs to join my lab. I have several NIH-funded positions to work either on Acinetobacter pathogenesis or OMV biogenesis in Bacteroides. Please RT.