Direct free energy evaluation of classical and quantum many-body systems via field-theoretic simulation pnas.org/doi/abs/10.107…

Beautiful

nature.com/articles/s4158…

Wow, beautiful work!

New paper alert! Just out in JBacteriology Eds featuring collaborations between three Northwestern CSB labs Tullman-Ercek Lab @jewettlab_NU and the Mangan lab. This work brings us a step closer to illuminating the process of bacterial organelle formation. doi.org/10.1128/jb.005… (1/8)

An artificial intelligence-based method can predict distinct conformational states of membrane transporters and receptors. elifesciences.org/articles/78549…

New paper from Per Jemth on the role of flanking linkers on affinity of IDP interactions ⬇️. Kinetics show that the linkers have a modest stabilizing effect due to non-specific hydrophobic interactions, not charge. doi.org/10.1016/j.jmb.…

O-GlcNAcylation modulates liquid–liquid phase separation of SynGAP/PSD-95 nature.com/articles/s4155…

Dynamic arrest and aging of biomolecular condensates are modulated by low-complexity domains, RNA and biochemical activity nature.com/articles/s4146…

Perspective by @PappulabWashU and myself on phase separation out in Molecular Cell today. If you wonder why disordered blobs should matter for biochemical function, I suggest you read this. Spoiler: Condensates are not disordered blobs.

Multiple ParA/MinD ATPases coordinate the positioning of disparate cargos in a bacterial cell biorxiv.org/content/10.110…

Protein structure can be predicted from a single sequence alone with high accuracy. Helixon Bio team have developed OmegaFold, achieving performance similar to RF and AF2's MSA versions. Only a single sequence is given as input. 1/5

Check out our newest paper from postdoc Bisco Hill describing the Mycobacterium marinum actin-based motility factor and its interesting ability to drive lipid droplet movement! rdcu.be/cQizA

New work from our lab ! Liquid Liquid phase separation of nanocatalysts and its impact on their catalysis.

Happy to share our latest paper in JBC (Journal of Biological Chemistry) Journal of Biological Chemistry describing how sub-stoichiometric Hsp104 controls amyloid formation from a yeast prion domain. Congratualtions to @SayantaIISERM Anusha Sarbahi Priyanka Madhu & Hema. doi.org/10.1016/j.jbc.…

Extremely happy to share our latest work on surface-enhanced vibrational Raman spectroscopy within biomolecular condensates 😁🥳

It's always a fantastic feeling to deliver introductory comments to start a conference #Nano@chembio2022

Thrilled to be awarded the 2023 Breakthrough Prize in Life Sciences together w/ Tony. An amazing journey we've been on, and the work of countless students, mentors, & colleagues, as well as the support of family & friends, have made this all possible.

Wondered about the role of phase separation on early Earth? Upon cyclic feeding of oligonucleotides, specific sequences get selected. A mechanism for the first self-replicating oligonucleotides? See arxiv.org/abs/2209.10672 Great collaboration with Braun+Mast-lab @emergenceoflife

A big thanks and congratulations to the team including #Moshekafri, #weronikapatena, Claire McWhite, Lianyong Wang, Martin Wühr, and Michal Breker!