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Super excited that our work on the rational design of 310-helical bundles is now out in nature! Congrats Prasun Prasun Kumar for this impressive piece you have led in collaboration with Clayden Group and Diamond Light Source! You can read it here: nature.com/articles/s4158…

Are you looking for robust antiparallel 4-helix coiled-coil modules for chemical and synthetic biology applications? We designed a common set of rules for antiparallel homotetramer, heterotetramer and single-chain protein. Find more in Chemical Science pubs.rsc.org/en/content/art…

The Woolfson thanksgiving dinner 2.0

Merry Christmas from the Woolfson lab!!! 🛼🥳❄️

Please retweet!📢📢 We are looking to appoint a BBSRC-funded post-doctoral research associate to work in the area of de novo enzyme design with alpha-helical barrels using computational design, protein biochemistry, and directed evolution. More details below

Friday submission day - Katherine and Rokas enjoying their celebratory cold beers at Bristol’s iconic suspension bridge, kudos to them both for their hard work!! Check it out biorxiv.org/content/10.110…

Thank YOU Billy Treacy for all of your incredible efforts as well!

Excited to pre-print our new work, applying protein to design to engineer an allosteric switch into kinesin-1 motors in vitro and in cells. biorxiv.org/content/10.110… Mark Dodding WoolfsonLab Bristol Biochemistry

Trimethyllysine Reader Proteins Exhibit Widespread Charge-Agnostic Binding via Different Mechanisms to Cationic and Neutral Ligands | J. American Chemical Society UNC-Chapel Hill @UNCResearch Waters Lab @ UNC #Trimethyllysine #Reader #Proteins #Agnostic #Binding pubs.acs.org/doi/10.1021/ja…

Excited to see our work in print at Nature Chemical Biology today! We are using protein/peptide design to manipulate the activity of kinesin-1 motors in cells. Mark Dodding WoolfsonLab Bristol Biochemistry nature.com/articles/s4158…

Check out this amazing woman's research!

Excited to share our latest designed A3B3 α-helical barrels, revealing how subtle the heptad register shift impact helix orientation. Well done to Joel Chubb Katherine Albanese and team WFU Chemistry Macquarie University Read more here biorxiv.org/content/10.110…

Proud to share this work led by Joel Chubb, who will excitingly be joining us as a postdoc in the new year! We can't wait for you to be here!!! 🥳🥳

The Albanese Lab is officially operational! Undergraduates Sam, Miko, Susy, and Wonhee preparing to express their first proteins 🧑‍🔬👩‍🔬

Looking for PhD students to join the new Cross lab, using protein engineering and design to manipulate intracellular transport! swbio.ac.uk/biomolecular-a… Project 62 Get in touch if you're interested in joining us! Working with WoolfsonLab Mark Dodding Bristol Biochemistry Bristol Chemistry

Our latest Primer on #ProteinDesign is out today! Thanks to all the authors working on this fascinating project. WoolfsonLab Albanese Lab @ WFU Katherine Albanese Sophie Barbe TBI ShunsukeTAGAMI Thomas Schiex INRAE Occitanie-Toulouse INRAE 📖:go.nature.com/4biQzoC

Extremely proud of these three newly minted WFU alums - Sam, Miko, and Katie. They've achieved so much over the past year, and I can’t wait to see all the incredible things they go on to do. Congratulations to the WFU Class of 2025! 🎓💛🖤 Wake Forest University WFU Chemistry