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Have a look at my #BBIConf2021 poster and all the other great posters of this year's Brainbox Initiative conference: brainbox-initiative.com/conference I am sorry if you couldn't find me on gather town, but I was busy finishing and submitting my PhD thesis manuscript! 🥳

If you like to work at the interface of chemistry and biology, this is an amazing opportunity for a PhD project working with @prothiwa

Our latest paper appears in ACS Chem Biol on novel modulators of the TRPM3 ion channel, with first authors Jan Pascal Kahler and Davide Aloi, and co-corresponding authors Joris Vriens and Marta Barniol-Xicota, who recently joined as assistant professor UPF Barcelona pubs.acs.org/doi/10.1021/ac…

Happy to see our work on TRPM3 channels in ACS Chem Bio, made possible by a great team !

🏹 Issue 7 is here! Steven Verhelst et al.'s article is featured on the front cover 😍 Azapeptide activity-based probes for the SARS-CoV-2 main protease enable visualization of inhibition in infected cells 🔗 ow.ly/WHSL50MTQt0 KU Leuven Weizmann Institute #ChemSciCovers🎨

Our recent paper on probes for the sars-CoV-2 main protease in chemical science is featured on the cover. The probe is fired as an arrow towards a heart-shaped Mpro carved on a tree with a virus-shaped crown. pubs.rsc.org/en/content/art…

Dedicated to Ben Cravatt for winning the Wolf Prize in Chemistry last year, we wrote a paper on a clickable fluorophosphonate probe - work from first author Jian Yang with help from Dimitris Korovesis, Shanping Ji, Jan Pascal Kahler and Roeland Vanhoutte. onlinelibrary.wiley.com/doi/10.1002/ij…

Our latest preprint is a collaboration with the group of René Zahedi - and deals with cleavable photoreactive groups. chemrxiv.org/engage/chemrxi…

This week, my lab exists for 15 years! I prepared a birdview talk for a half-day anniversary meeting tomorrow with lots of former and current lab members. I'm happy that several former members agreed on giving updates on their endeavors, and Laura Edgington-Mitchell for giving a guest talk!

My lab's latest paper deals with novel phosphonate and phosphinate esters as activity-based probes for furin. Congrats to Shanping, for whom it is his 1st first author paper. It also happens to be my 100th publication! pubs.rsc.org/en/content/art…

Advances in Ultrahigh Throughput Hit Discovery with Tandem Mass Spectrometry Encoded Libraries | Journal of the American Chemical Society Sebastian Pomplun Leiden Science LACDR Universiteit Leiden #HighThroughPut #HitDiscovery #MassSpec #Tandem #JACSPerspective pubs.acs.org/doi/10.1021/ja…

Just accepted: our latest manuscript on novel rhomboid protease inhibitors. We screened a set of oxo-beta-lactams against model rhomboid E coli GlpG and found several inhibitors with micromolar apparent IC50. …mistry-europe.onlinelibrary.wiley.com/doi/10.1002/cb…