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excited to announce our new paper in Cell on ARC-well by Kaile Wang Tapsi Kumar, PhD, on a new single cell DNA-seq nanowell method that we applied to study DCIS and recurrences, revealing an evolutionary bottleneck during progression MD Anderson Cancer Center sciencedirect.com/science/articl…

Congrats to the teams at MD Anderson Cancer Center, UC Irvine, and others on publishing the first Human Breast Cell Atlas in @nature! This reference is an unprecedented effort that profiles 700,000+ cells and will aid in creating the Human Cell Atlas’s first draft. nature.com/articles/s4158…

Now online! Archival single-cell genomics reveals persistent subclones during DCIS progression dlvr.it/SthWxb

Now online Cell from Nicholas Navin MD Anderson Cancer Center & Cancer Grand Challenges PRECISION consortium: Archival single-cell genomics reveals persistent subclones during DCIS progression cell.com/cell/fulltext/… This study introduces Arc-Well, which allows single cell DNA copy number

FFPE profiling techniques are the new frontier! Ground breaking work by our talented team led by Kaile Wang !

Read about our latest advances in cancer research, including: ▪️ Single-cell sequencing technology for analyzing FFPE samples ▪️ A study of long noncoding RNAs in #glioblastoma ▪️ Pan-cancer studies of National Cancer Institute proteogenomic dataset bit.ly/3YAVsmw Nicholas Navin

Excited to share Monopogen that performs SNV calling from single-cell DNA/RNA/ATAC-seq data, to enable cellular population genetics. nature.com/articles/s4158…. Thanks Rui Chen, Nicholas Navin, Shyam Prabhakar Lab, Li Ding, Chan Zuckerberg Initiative CZI Science, #HTAN, Nature Biotechnology collaborators/friends.

A recent Cell paper from the PRECISION team describes its development of Arc-well, a high-throughput single-cell DNA-sequencing method for profiling genomic copy number from archival formalin-fixed paraffin-embedded (FFPE) tissues ⬇️ cell.com/cell/fulltext/… (£/$) (1/3)

We are recruiting assistant/associate level faculty in the new Systems Biology department at MD Anderson Cancer Center MD Anderson Cancer Center . Come join our department, with brand new offices and spectacular views of downtown Houston. mdanderson.org/about-md-ander…

NEW content online! Revealing genomic secrets of archival FFPE samples dlvr.it/T5Fz41

What a great way to end the day at the AACR #AACR24 that with #singlecell DNA sequencing scDNA-seq data by Nicholas Navin from MD Anderson Cancer Center !

Really excited to publish our recent work in Nature Communications Nature Communications on the spatial heterogeneity in Hepatocellular Carcinoma. nature.com/articles/s4146… with Xiaodong Liu, Neslihanky and LiangMa_IOZ and colleagues.

In this #ToolsoftheTrade article, Kaile Wang describes the development and use of #Arcwell, a high-throughput #singlecell #DNAsequencing method tailored to analyze archival FFPE materials. go.nature.com/43Xkn6G

Thrilled to announce I’m opening my new lab today at the Institute of Biochemistry and Cell Biology (Shanghai), Chinese Academy of Sciences. My lab will focus on developing new single cell and spatial multiomics tools to understand cell dynamics and disease progression eg. cancer

New paper from our group in nature by Yiyun Lin @junkewang Kaile Wang and team reporting the unexpected discovery of aneuploid epithelial cells (3%) in normal breast tissues from healthy women raising the question of when is cancer really cancer? nature.com/articles/s4158…

We’re hiring highly motivated postdocs! If you’re interested in developing and applying single-cell multiomics and spatial multiomics technologies to study cancer initiation, progression, and treatment-induced resistance, please feel free to DM me.