KangBo Ng
@kangbo_ng
PhD candidate in the @goehring_lab at @TheCrick. Interested in pattern formation during development. 🪱🔬🖥️👨🏻🔬
ID: 1493889186750992389
https://www.crick.ac.uk/research/labs/nathan-goehring 16-02-2022 10:05:25
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Design principles for selective polarization of PAR proteins by cortical flows. A new study from Rukshala Illukkumbura @rukshala_i, Nathan Goehring Goehring Lab and colleagues The Francis Crick Institute Imperial Science: bit.ly/42pazjg #Development #Biophysics #Cytoskeleton #Polarity
New preprint from @tsmbland The Francis Crick Institute reveals a #ubiquitin-independent role for a RING domain in promoting membrane-dependent dimerization which allows specific & cooperative #plasmamembrane #PARprotein recruitment during #cellpolarity in #celegans 👉 biorxiv.org/content/10.110…
New Goehring Lab pub from KangBo Ng The Francis Crick Institute reveals furrow-directed actomyosin flows transport PAR-3 into the nascent cell contact to link #cellpolarity & #celldivision in the #Celegans embryo. Now w/ more #FLUCS! 🙏 @kreysinglab Current Biology cell.com/current-biolog…
Nice work from my neighbours in Goehring Lab at The Francis Crick Institute Nonlinearity in molecular mechanisms provides developmental robustness C.elegans polarity axis specification is resistant to variations in strength of symmetry-breaking cues & PAR protein dosage biorxiv.org/content/10.110…
I am excited to announce the publication of our manuscript out today, with Philippe Gui, Charles Swanton, Swanton Lab, Bivona Lab, @Downwardlab, and The Harris Lab! 🧵 1/15 nature.com/articles/s4158…
Hot off the press in Biochemical Journal where we discuss new insights into aPKC membrane targeting. These PKCs do not bind DAG to get recruited, instead they fold up their regulatory elements exposing a single membrane binding platform! read on here👇doi.org/10.1042/BCJ202…
🚨Meeting alert! Do you study cell lineages? In development, cancer, growth, regeneration? Join our The Royal Society meeting “Cell lineages across scales, space & time": barcoding, somatic tracing, imaging, modelling. Submit abstract, engage with leading speakers & win prizes!
Our latest from James Briscoe lab: How temporal & spatial pattering cues are integrated in the vertebrate neural tube to organise cell type generation during development. biorxiv.org/content/10.110…
In our latest pre-print Yifan Zhao, @gavinpaulkelly and @gantasperez reveal that mild hypoxia is a physiological consequence of growth in Drosophila imaginal discs. Check the work in biorxiv.org/content/10.110…
Pumped to share our latest and first (!) work from Rashmi Priya @rashmi-priya.bsky.social lab The Francis Crick Institute! Using the powers of #zebrafish, we uncover how multiscale mechanochemical coupling drives morphological and functional maturation of the developing heart 🫀 Stay tuned for the🧵 biorxiv.org/content/10.110…
Did you know cell filaments love to treadmill? 🔄 They grow and shrink on opposite ends and burn energy doing it! But why? How does it drive self-organisation and bacterial division? Dive into our new publication ft. Andela Saric @nartimsoole @seamus_holden labs to find out! 🧫🔬🖥️
NEW from us The Francis Crick Institute! Capture, mutual inhibition and release mechanism for aPKC-Par6 and its multi-site polarity substrate Lgl | bioRxiv #Science #Research #StructuralBiology #CryoEM #Crystallography #Polarity #Cancer biorxiv.org/content/10.110…
4-year PhD and post-doctoral positions Goehring Lab The Francis Crick Institute combining advanced cell biological, biophysical, and theoretical approaches to uncover the design principles of cell polarity and fate specification in C. elegans. crick.wd3.myworkdayjobs.com/External/job/L… crick.ac.uk/careers-study/…
