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🦠 A low-pathogenic AIV, (H1N1), shows high virulence in mice & ferrets, with human-like α2,6-SA binding, replicates efficiently in human A549 cells. Zoonotic potential? sciencedirect.com/science/articl…

🦠 New findings on #H9N2: PB2 627V + HA 217 deletion synergistically boost virulence in mice. Despite impaired entry & budding, enhanced polymerase activity & strong IFN response drive lethality. All isolates belong to the G57 genotype sciencedirect.com/science/articl…

🚨 First human case of #H10N5 #influenza reported in China (Jan 2024). 🧬 Reassortment with wild bird AIVs (H10N7, H12N5) likely. 🗺️ Clustering by bird migratory flyways hints at a new AIV evolution hotspot in NE Asia. sciencedirect.com/science/articl…

A Texas dairy cattle H5N1 shows alarming traits: 🧫 Grows faster in human lung cells than older strains 🐭 Severe disease & brain infection in mice blocks key innate immune responses (RIG-I, MDA5) Despite mild human cases, it has high pathogenic potential nature.com/articles/s4159…

📉 The 2023 H5N1 epidemic caused near-total pup mortality in southern elephant seals at Península Valdés, Argentina. Adult female deaths have the most severe & lasting impact—decades needed to recover to 2022 levels. onlinelibrary.wiley.com/doi/full/10.11…

🚨 Detection of HPAI H7N6 in New Zealand poultry wahis.woah.org/#/in-review/60…

🐔🧫 Kappa Flu Partner EMC established Long-term chicken tracheal organoids to enable realistic studies of avian influenza virus replication and tropism. Self-renewing, mucociliary, and virus-ready. virologyj.biomedcentral.com/articles/10.11…

📊 Kappa Flu Partners contributed to the EFSA-ECDC overview (Dec 2024–Mar 2025): 743 HPAI H5 detections across 31 European countries – mostly H5N1 in wild birds. First cases in domestic cats & wild carnivores since spring 2024. pmc.ncbi.nlm.nih.gov/articles/PMC11…

A new paper in cooperation with Kappa Flu Partner EMC found one mutation (Q226L) can shift HPAI H5N1 2.3.4.4e virus to bind human-type receptors — a critical step toward zoonotic potential 📍 Highlights urgent need for surveillance & pandemic preparedness. pnas.org/doi/10.1073/pn…

A new paper in cooperation with Kappa Flu Partner EMC: ⚠️ HPAI H5 virus detected in 10 dead Northern Fulmars (Fulmarus glacialis) in the Netherlands (Jan–Feb 2024). 🔬 Half were H5N5 with mammalian adaptation markers. meridian.allenpress.com/jwd/article/do…

🐄📉 HPAI H5N1 outbreak in Michigan dairy cattle led to: ⚠️ 32% herd affected over 45 days 🥛 Avg. milk yield ↓ 5.7% (peak ↓ 22%) 📊 $504 loss/affected cow | $79K/500-cow herd 🧾 Milk loss = 92% of total cost 🔗 sciencedirect.com/science/articl…

A poultry HPAI H5N1 vaccine showed safe & protective immune responses in critically endangered California condors. 💉 80% responded within survival-associated antibody range. ➡️ Now part of a condor protection strategy. wwwnc.cdc.gov/eid/article/31…

🐔🦠 AIV surveillance in China (2021–2023) Over 8,000 environmental & 800 human samples screened in 3 regions: 🔹 H9 was most prevalent (18.4%) 🔹 H5 peaked in Chongqing (13.5%) 🔹 No human AIVs found 👉 Boost poultry vax, tighten LPM biosecurity researchsquare.com/article/rs-604…

🚨 How many ducks must die before HPAI is suspected? New study identifies 0.25% daily mortality or an 8-fold increase over baseline for 2 days as effective thresholds in mule ducks—enabling faster outbreak detection. veterinaryresearch.biomedcentral.com/articles/10.11…

A new study shows H4N1 avian influenza virus can bind to human cells, cause pneumonia in mice, and rapidly adapt to grow better in human tissues. virologyj.biomedcentral.com/articles/10.11…

🚨 WOAH report: Detection of HPAI H7N6 in New Zealand poultry farm Origin likely from wild birds; >194,000 birds affected Depopulation, movement control & 10 km surveillance zone in place. wahis.woah.org/#/in-review/60…

🇬🇧 #HPAI H5N5 update (UK, wild birds) 🔹 Ongoing event since Oct 2024 🔹 Latest: Red Kite found dead (Nov) confirmed HPAI+ 🔹 Total affected: 414 wild birds 🔹 Most impacted: Herring Gulls, Pheasants, Buzzards wahis.woah.org/#/in-review/59…

🇸🇪 #HPAI H5N1 update (Sweden, wild birds) 🔹 Ongoing outbreak since Jan 2025 🔹 Latest data: 9 new wild bird cases (Greylag Goose, Mute Swan, Peregrine Falcon, etc.) 🔹 Total affected so far: 97 birds wahis.woah.org/#/in-review/62…

🚨 First-ever outbreak of HPAI H5N1 in Liberia (poultry) 📅 Start: Feb 3, 2025 | 🐔 26,000 "Vaccinated" birds 🔍 Likely causes: wild birds, illegal animal movement, fomites 🦠 Immediate notification validated Apr 17 wahis.woah.org/#/in-review/64…

🇳🇱 Netherlands: HPAI H5N1 in 41 wild bird species 📍 Wetland-origin case; ongoing outbreak 🦢 Most affected species: Barnacle Goose, Greylag Goose, Herring Gull, Common Buzzard wahis.woah.org/#/in-review/60…