
KelvinTuong
@kelvintuong
Immunology and bioinformatics. TCR/BCR, B cells and Macrophages. Senior Research Fellow/Group Leader.
bsky.app/profile/kelvin…
ID: 941840439144890368
https://github.com/zktuong 16-12-2017 01:20:34
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Gfi1 controls the formation of effector-like CD8+ T cells during chronic infection and cancer nature.com/articles/s4146… Nature Communications


GFI1-driven transcriptional and epigenetic programs maintain CD8+ T cell stemness and persistence Nature Immunology nature.com/articles/s4159…



Clonal tracing with somatic epimutations reveals dynamics of blood ageing nature Alejo Rodriguez-Fraticelli, PhD Indranil Singh nature.com/articles/s4158…



SUM-seq out Nature Methods! 🚀 Ultra-high-throughput Multiplexed snATAC+RNA Used to: ⏳ link temporal macrophage GRNs to immune disease genetics 🩸 map T cell regulatory landscapes 🧬✂️ dissect TF function in hiPSC differentiation via CRISPRi/a screens doi.org/10.1038/s41592… 🧵

Thrilled to see #SAVANA out in Nature Methods🥳 SAVANA detects haplotype-resolved somatic SVs and copy number aberrations (SCNAs) and infers tumour purity & ploidy in clinical samples using long-read sequencing with or WITHOUT a matched germline control 👇nature.com/articles/s4159…




🔎 We’re back with another MiLaboratories Research Spotlight! Enabling next-generation engineered TCR-T therapies based on high-throughput TCR discovery from diagnostic tumor biopsies Neogene, an AstraZeneca company, has developed a new TCR discovery platform - a step forward


1st paper out as the senior author, fittingly it is the revamped scRepertoire: building a more comprehensive and efficient single-cell immune profiling ecosystem!! Large thanks to my co-authors KelvinTuong and others Paper: journals.plos.org/ploscompbiol/a… Repo: github.com/BorchLab/scRep…


An atlas of the cellular and molecular landscape of the juvenile idiopathic arthritis synovium defines tissue niches associated with disease severity Science Translational Medicine science.org/doi/10.1126/sc… Lucy Wedderburn chrissyb


I'm thrilled to share our new study out in Nature Medicine! We show that a blood test can estimate how aged or youthful one’s organs are and that these organ ages predict future disease and lifespan. Final paper from my PhD in the Tony Wyss-Coray lab. 🧵1/12 🔗 nature.com/articles/s4159…


Excited to share a milestone published in Nature Medicine from our decade-long effort to build The Human Phenotype Project, a unique longitudinal cohort with unmatched depth of clinical and multi-omic profiling, enabling truly predictive, personalized medicine. Led together with
