After 7 years, thrilled to finally share our #MICrONS functional connectomics results! We recorded activity from ~75K neurons in visual cortex in a single mouse, then mapped its wiring using electron microscopy. To systematically characterize neuron function, we built the first

Congrats to Hysell Oviedo, PhD, who has been installed as the Roger M. Perlmutter Career Development Assistant Professor of Biomedical Research. Read more about her research journey that started with a lecture on echolocation in barn owls and bats. neuroscience.wustl.edu/hysell-oviedo-…

Most people don’t understand how *new* most cancer treatments are. The treatment that cured my lymphoma was developed when I was a teenager. The treatments that will cure our children’s cancers are being put on hold right now.

Nobel laureate Bill Kaelin on Killing the Science Golden Goose. "This is especially worrisome because becoming a scientist is largely taught by apprenticeship, with each generation teaching the next. We risk losing the next generation, our “seed corn”" amjmed.com/article/S0002-…

We need bodyoids with brainoids inside!

Beautiful study by my colleagues showing the synaptic mechanisms for ketamine "anti-anhedonic" effects. Federica Lucantonio and Marco Pignatelli

Cancer muscle wasting-associated apathy is result of tumour-induced inflammation & brain circuitry interaction 📷 Xiaoyue Aelita Zhu & Sarah Starosta et al Kepecs Lab Marco Pignatelli Tobias Janowitz WashU Medicine Neuroscience in Science Magazine ➡️ bpod.org.uk/archive/2025/5… + Ruth Williams

Meet the Area Postrema!

Why does CAR T-cell therapy cause "brain fog"? In a landmark study Michelle Monje🎗️ 🟦 et al. show white-matter inflammation drives cognitive deficits. Blocking these, either resetting microglia or dialing back their chemokine response restored myelin & rescued attention+memory!

The most vocal ‘protector of minorities’, sitting on billions of private dollars, is the first to retreat because of the risk of tax on their endowment. Ridiculous and shameful!

This chart made by Peter Gleick shows the proposed cuts to science graphically. This is bad for America. Please ask Congress to save science. #FundingScienceSavesLives

Can’t believe #GRCPsychedelics is happening in two weeks! We reached capacity attendance – sorry we could not accommodate everyone. We look forward to seeing many of you at the meeting. w/ Vlad Vyazovskiy Vidita Vaidya Dr Melissa Herman

Reducing animal use is a worthy goal but mechanistic discovery, the engine of biomedical progress, still requires animal models. Translation is vital and challenging and could be improved with these initiatives. Just don’t conflate the two.

We worked so well as a team for the #GRCPsychedelics Vlad Vyazovskiy Dr Melissa Herman Vidita Vaidya and congrats to Boris D Heifets and Mikael Palner, who will be the future vice-chairs!

Grateful to Meg Tirrell and CNN for covering this story. My NIH grant to study hearing loss was abruptly canceled, then restored by a court, but NIH hopes to terminate the grant AGAIN(statnews.com/2025/07/06/hhs…), creating massive uncertainty for my trainees. We're in a golden age

Wow, this is truly exciting! Congrats to Prof. Kevin J. Tracey, MD and the whole team...

#ChatGPT5 is a letdown, not because it's not AGI, but because it's slow and then shy about discussing molecular biology "for safety reasons" Just canceled; Gemini's looking better