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Excited to share our latest work describing MN714 – first-in-class covalent inhibitor of SOCS2, a substrate adaptor of Cul5 E3 ligase. A >5-years long journey in the making full of twists and surprises. Please Retweet! Thread below 1/13 doi.org/10.26434/chemr…

Excited to share our latest review in Current Opinion/Research in Structural Biology We take a snapshot on current solution-based structural biology methods and studies of ternary complexes formed by PROTACs and molecular glues, and offer a forward-looking perspective of where the field may go next

Here is the Jan 2023 edition of the CeTPD journal club edited by Yuting Cao, Sohini (she/her) and me... it's slightly late, but rich in features!

Finished some photos 📸 for #EUbOPEN2024 in Centre for Targeted Protein Degradation for EUbOPEN 🇪🇺 organized by Kevin Haubrich ⌬ Dylan ⌬ Alex Hallatt - so grateful to them for their efforts and flawless execution. Got to reunite with old #chemistry friend Claudia Diehl too. 🏴󠁧󠁢󠁳󠁣󠁴󠁿#ubiquitin #tpd

Leaving Dundee for the last time after living here for 4.5 years. Even the weather is appropriately sad. I will miss this shithole.