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Delighted to annouce our work is out Nanoscale journal family! A big team effort KeyserLab Laser Analytics Group (Kaminski Lab) Molecular Neuroscience Group Holcman Nathalie ROUACH Diversity of dynamic voltage patterns in neuronal dendrites revealed by nanopipette electrophysiology pubs.rsc.org/en/content/art…

Check out our new paper in Nanoletters led by the talented Yunxuan Li, where we use DNA nanostructures and nanopore signals to characterize the physical properties of DNA! Nano Letters KeyserLab #dna #nanotech #nanopores pubs.acs.org/doi/10.1021/ac…

Latest review on nanopore protein sequencing, have a look!

Check out my first first author paper of my PhD out now in Nature Biomedical Engineering ! We utilize solid state #nanopore sensing and #dna #nanotech as a way to assay #CRISPR #Cas9 binding efficiency!

End-of-summer barbecue and foosball at Ulrich’s house 🍖 🌱 ⚽️ 🧬

In a paper in Nature Nanotechnology, researchers Cambridge University went fishing for viruses using programmable DNA nanobait technology. KeyserLab bit.ly/3Zu7M8L

Finally we are happy to announce that in the last week of September we spent an amazing time with the members of the DYNAMO consortium. Students under the guidance of professionals in the field of #nano presented their projects and defined goals for the future #DYNAMO #nanopores

Four of our physicists have been recognised in the Institute of Physics Awards 2023 for their outstanding contribution to experimental physics, public engagement, soft matter physics, and atomic physics. Congratulations to them!🏅 Follow the thread to learn about the winners and their awards 🧵

With Uli Keyser you always get the combination of cool physics and application driven assay development.

Our paper is finally out in JACS! Exciting to see this collaboration (KeyserLab,Vendruscolo Lab) develop into a project with a lot of potential impact in both the fields of #protein #sensing using #nanopores and PD #diagnostics and #therapeutics 🧬💊 pubs.acs.org/doi/full/10.10…

Multiplexed Digital Characterization of Misfolded Protein Oligomers via Solid-State Nanopores | Journal of the American Chemical Society Cambridge University Cavendish Laboratory Maxwell Centre #digital #Characterization #Misfolded #Protein #Nanopores pubs.acs.org/doi/10.1021/ja…

While characterising harmful oligomers is crucial to developing accurate diagnoses and treatments for diseases involving misfolded proteins, like Alzheimer's, identifying them in complex mixtures has remained challenging. This new test may change that. chemistryworld.com/news/nanopore-…

Our latest paper collab with lots of great colleagues is now available in ACS Analytical Chemistry Journals, extending our solid-state #nanopore approach to analyzing the size distribution of heavy-chain modified #hyaluronan from physiological biofluids. pubs.acs.org/doi/full/10.10…

Check out our new article in Nature Communications ! We use RNA nanotechnology and nanopore sensing to assess transcript size and heterogeneity. We identify premature transcription termination, study rolling circle transcription and describe enzymatic processivity. Special thanks to

Great second session at Cambridge Infectious Diseases IRC Annual #Symposium Kate Baker KeyserLab Chris Ruis Andrew Conlan Robinson College

🥳 New paper from the group! Casey Platnich has shown with nanopore sensing that the denaturing properties of urea can be used to break up RNA secondary structure and allow DNA staples to bind without heating! 🧬 Check out the paper in J. Am. Chem. Soc. here:tinyurl.com/5bkx7nzv

In a study led by Filip Boskovic we examined how the electrophoretic transport of RNA:DNA and DNA through nanopores depends on the contour length rather than the number of base pairs. Nice blend of experiments and simulations! AksimentievLab ACS Nano 🧬🕳️⚛️ Cambridge University

pre-print alert!🚨 Filip Boskovic and I’s collaboration from our time in the ⁦KeyserLab⁩ using #nanopores for serovar discrimination with single base pair specificity of rRNA is now on biorxiv! 🦠 biorxiv.org/content/10.110…

Leveraging rRNA's 100,000-fold higher abundance over rDNA, we developed a one-pot method for RNA isolation, enrichment, and assembly of RNA identifiers, enabling detection of pathogenic bacteria and AMR variants without the need for amplification! 🧬🥼 Sarah Sandler KeyserLab

(1/n) How do we detect modified RNA, and DNA with the help of template-free, catalyst-free click chemistry and solid-state nanopores? 🧪🥼🧬🕳️