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Using population health databases from Ontario, Canada, investigators found that children surviving AKI without acute KRT were at higher long-term risk of CKD, long-term KRT, hypertension, and subsequent AKI compared with hospitalized children without AKI bit.ly/JASN0445

Interested in learning how to design and operate clinical trials for pregnant people and kids? 🤰👶🧒 Apply for an IMPaCT training award at impactrials.ca/awardinfo! Applications are open now, so don't miss out – submit by 5 PM CT on October 18, 2024!

Meet IMPaCT Fellow Cal Robinson ! Through his research, Cal aspires to advance the evidence-based treatment of pediatric kidney diseases, prevent adverse long-term outcomes, and minimize disease burden. Learn more about Cal’s project here: impactrials.ca/cal-robinson

Long-Term Kidney Outcomes after Pediatric Acute Kidney Injury #AKI ow.ly/3G7F50SUxEV JASN_News

Children with posterior urethral valves are at long-term risk of CKD, kidney failure, and hypertension. One-third develop major adverse kidney events over median 16.6 year follow-up. Kidney health surveillance into adulthood with improved transition planning is needed!

Long-Term Kidney Outcomes in Children with Posterior Urethral Valves #PUV JASN_News ow.ly/Pqz450T4EnC

Using population-based health administrative databases, study investigators found that 1/3 of children with posterior urethral valves develop major adverse kidney events (death, kidney failure, or CKD) by early adulthood, compared with 1% of the general childhood population.

Excellent poster by Cal Robinson et al on a target trial emulation of cyclophosphamide vs CNIs in #nephroticsyndrome ! #ASNKids24 American Society of Pediatric Nephrology American Society of Nephrology

Amazing to see a childhood nephrotic syndrome RCT in the #ASNKids24 ⁦American Society of Nephrology⁩ late breaking trials session! So exciting to see RCTs starting to emerge to improve treatment for these children

Long-Term Kidney Outcomes after Pediatric AKI ca. 2024 from JASN_News #Nephpearls #KidneyWk #BestofJASN #VisualAbstract by Paolo Nikolai So 👉 pubmed.ncbi.nlm.nih.gov/39018120/

How can simulation be used to improve the design adaptive clinical trials? Read our review article just published in JASN_News to find out! Big thanks to co-authors Rulan Parekh Yongdong Ouyang Eddy Fan Brian Cuthbertson and Anna Heath. journals.lww.com/jasn/citation/…

AKI affects a growing number of children and neonates and is associated with high morbidity, mortality, and health care expenditure. In this issue of JASN, Robinson et al. present the findings of a large cohort study on the long-term outcomes of AKI in hospitalized children who

I have made the jump over to BlueSky - follow me there at the same handle Cal Robinson bsky.app/profile/kidney…

Steroid-sparing immunosuppression is used in 50% of children w/nephrotic syndrome, but rates & predictors of prolonged remission after cyclophosphamide & tacrolimus are uncertain. Read this Original Article for more. link.springer.com/article/10.100…

Central venous catheter–related bloodstream infections (CRBSI) are common in children receiving hemodialysis & cause significant morbidity & healthcare costs. Read this Original Article on use of 4% tetrasodium EDTA (KiteLock™) to prevent CRBSI. link.springer.com/article/10.100…

Incidence and Risk Factors for #Hypertension among Children with #Nephrotic Syndrome ⁦JournalofPediatrics⁩ #HTN #Nephrotic sciencedirect.com/science/articl…