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CollectorMask The main reason I'm posting this is to allow folks to understand how selegiline stands in the way of brain deterioration and age-related dementias, now possibly including Alzheimer's disease. I've posted on this and the general topic of forestalling brain deterioration. I hope

CollectorMask People surviving to advanced ages are sometimes fortunate to retain serviceable mental faculties. Some has to do with brain heuristics and plasticity that serve as a stand-in for what is gone. Lost neurons, damaged white matter connections, lower volume are all practically a

Dr. Thomas Ichim Yason After 22 years at 1 gram/daily, I'm especially in support of metformin. It's such an unassuming small molecule drug; looking more closely seems to yield additional mechanisms of action. For example, I recently discovered that metformin also acts as a GLP-1 agonist. Post age 40, I

Here is the Q&A portion of my Vitalist Bay presentation on Brain Health and preservation. Clips with their often inaccurate, gratuitous subtitles, we shall forgo this round. Main long-form prez to follow. Enjoy. Oh, and since it's a Q&A, feel free, as well. 😀

Right . . . and avoid the app that wakes you with a notification that your brain just shrunk. . . . 'Normal' brains shrink 1-2 percent per year after age 35-37. White matter with it, and often greatly enlarged ventricles—still often seen as normal. Not I.😌

Karl Pfleger Radiologist notes on nearly all joint imaging most often includes a default comment regarding OA/deterioration on most anyone past the age of 20. That's because joint degradation is like mileage. True, whether or not it's manageable/mitigable or can be supported by muscle health

Here is my Vitalist Bay presentation on brain health and neuron preservation. This information is not the usual 'diet, sunshine, exercise.' Selegiline is a critical intervention that those with aspirations of long life will ignore possibly at their peril. I am the quintessential