
Kirchhausen lab
@kirchhausenlab
Research group @harvardmed using advanced imaging to follow subcellular dynamics from molecules to multicellular organisms
ID: 1006635701809672193
https://kirchhausen.hms.harvard.edu/research 12-06-2018 20:33:48
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Check out our latest collaboration with BlacklowLab! Great work led by Alex Martin!

Stunning 4D imaging of Notch signalling events at physiological levels using Lattice Light Sheet Microscopy. Very proud of this Blacklow Lab collaboration led by @GuScanavachi & Lena Tveriakhina!

How much can be extracted from diffusion of single molecules? Here we show diffusion can reveal viral escape to the cytosol, the cellular location of clathrin coated pits, and can encode biomolecular identity. Great collab Nikos Hatzakis lab Department of Chemistry, University of Copenhagen and Kirchhausen lab at Harvard Medical School

Detection of viral entry solely by variation of diffusional behavior! Check our #DeepSPT on biorxiv.org/content/10.110… showing how our #deeplearning toolbox captures biology using motion only. Work in Department of Chemistry, University of Copenhagen, @ISBUC with Kirchhausen lab in Harvard Medical School #fluorescensefriday

In our preprint #DeepSPT we show #Rotavirus's escape to the cytosol can be detected solely by change in diffusion. For more examples of capturing biology by motion: biorxiv.org/content/10.110…. Nikos Hatzakis lab Department of Chemistry, University of Copenhagen Kirchhausen lab Harvard Medical School ISBUC #deeplearning #FluorescenceFriday

Intrinsically perforated endo-lysosomes in neurons are crucial for alpha-syn aggregation. Check out our latest preprint. Another great collaboration with Nikos Hatzakis lab lab. biorxiv.org/content/10.110… Harvard Medical School Boston Children's @HarvardCellBio


Neuronal constitutive endolysosomal perforations enable α-synuclein aggregation by internalized PFFs, say Anwesha Sanyal, Tom Kirchhausen and colleagues Kirchhausen lab Harvard Medical School: hubs.la/Q030wlg10 #Neuroscience #Organelles #Trafficking #Disease

