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Just a few weeks until the National Inventors Hall of Fame® Induction Ceremony! Take another look at this year’s class of Inductees before the big event on May 9. bit.ly/2H9x0Si #NIHF2024

In just 10 years, 2024 Inductee David Klenerman & co-inventor Shankar Balasubramanian transformed a concept on paper into pioneering the Sequencing-by-Synthesis method for #DNA sequencing. Explore the remarkable journey of this newest Inductee! #NIHF2024 bit.ly/4aNmDA6

Having a lifelong affinity for science, #NIHF2024 Inductee David Klenerman pursued chemistry Cambridge University, graduating with a bachelor’s degree in 1982. Returning in 1994, he currently serves as a professor of biophysical chemistry & is a group leader at the UK Dementia Research Institute.

Different Viewpoints: The David Klenerman and Shankar Balasubramanian Story 🧬 youtu.be/FgGO2QtudAM?fe… via Inventors HOF

I am recruiting for a PhD vacancy in developing computational tools for single molecule imaging with applications to dementia. For information: daniallab.com/vacancies/vaca… Please retweet KlenermanLab Steven F. Lee Achillefs Kapanidis Mark Wallace Christophe Leterrier Aleks Ponjavic

A new pilot study from KlenermanLab et al tested an antibody-based single-molecule pulldown assay to quantify salivary α-synuclein & amyloid-β peptide aggregate numbers (#Parkinsons & #Alzhiemers); Saliva aggregates retain relevant structural information academic.oup.com/braincomms/art…

Interesting: KlenermanLab et al establish an ultra-sensitive single-molecule pull-down immunoassay combined with dSTORM microscopy assayed human post-mortem brain, serum & CSF of #Parkinsons, #Alzheimers & elderly individuals for inflammasome ASC specks nature.com/articles/s4146…

Scientists led by KlenermanLab have developed a new biomarker to measure brain inflammation in Alzheimer's & Parkinson's 🧠 👏 It could improve diagnostics and help test new therapies in clinical trials: 👉 buff.ly/4i8aycL

SynPull: An advanced method for studying neurodegeneration-related aggregates in synaptosomes using super-res microscopy by Shekhar Kedia, Emre Fertan, John S H Danial, David Klenerman KlenermanLab et al at Cambridge University UCL University of St Andrews dlvr.it/THYqLv

Wow! First session at #ADPD2025 & Florence Layburn Florence Layburn from the KlenermanLab is sharing new data using their new SIMPull method to look at the detection of soluble Tau aggregates in #Parkinsons. Very impressive presentation from this young PhD student!

KlenermanLab out in force AD/PD - Advances in Science & Therapy #ADPD2025 🇦🇹 Look out for talks from Beatrix & Dorothea tomorrow 👀

Witnessing an unforgettable moment when Prof Sir David Klenerman KlenermanLab and Prof Sir Shankar Balasubhramaniam took us all through a journey of a few decades. The ups and downs, the importance of socialization, and most importantly the power of simple ideas -(1/2)

What a wonderful talk!! Dorothea Boeken (KlenermanLab) Cambridge University, advanced single molecule-super resolution Tau image assay. UNVEILING THE MOLECULAR LANDSCAPE OF TAU AGGREGATES IN ALZHEIMER’S DISEASE AND OTHER TAUOPATHIES. UK Dementia Research Institute #ADPD2025 AD/PD - Advances in Science & Therapy 🎉

➡️ Read our new paper here: pmc.ncbi.nlm.nih.gov/articles/PMC12…

🚨 NEW PAPER ALERT 'Detecting alpha-synuclein aggregates with small molecules on single-molecule array': doi.org/10.1039/D4SC07… Excited to share this KlenermanLab & Hunter Lab Cambridge Chemistry collaboration. 1/🧵