🔥The 9th Round of Easy Loan, Earn $40 Reward is in progress❗️ ⏰ Promotion Period: January 15th - Feburary 15th, 2025 👉 Register now and check more details at gate.io/campaigns/358

🎉🥳Our 6th OHBM Diversity and Inclusivity Committee Symposium w/ Lucina Uddin, Julia Kam, and Davynn Tan on "Diversity, Equity, and Inclusivity in Artificial Intelligence and Neuroimaging" has been accepted for #OHBM2024, featuring a fantastic lineup: Sarah Yip , Zhiyi Chen, Jingwei Li, and Jakub Kopal !

Delighted to be awarded #msca postdoc fellowship by Marie Skłodowska-Curie Actions to study genetics of human development at Norment with Ole Andreassen. Big thanks to Universitetet i Oslo Dennis van der Meer @ParekhPravesh for the support.

16p11.2 BP4-5 #CNVs are associated with broad and highly heterogeneous phenotypic alterations, but can we learn about the mechanisms behind this #pleiotropy? 🧬🕵🏻‍♀️ This is the question that our new preprint addresses!👇🏻🧵 rb.gy/qx6xjc #RareDisease #GenomicDisorder 💫

With Danilo Bzdok, we leveraged rare genetic mutations (#CNVs) to revisit structural brain #asymmetry. Planum temporale emerged as especially susceptible to deletions & duplications of specific gene sets. nature.com/articles/s4146…

🗞️Excited to share our latest preprint on the shared genetics of common epilepsies and general cognitive ability (COG). doi.org/10.1101/2024.0… 🧬We showed almost complete overlap between common epilepsies and COG, and identified 66 distinct loci shared between these phenotypes.

Fresh paper just out, driven by Gesa Hartwigsen + Jakub Kopal: Human-specialized neural circuits are separated from ordinary cognition via causal evidence from localized brain tissue damage repository Posterior probabilities are reported for the hemisphere-specific

New post-doc positions in our team. Please DM if you are interested.

👏👏Finally out!! Our new study called copy number variants in ABCD study, identified genetic associations with dimensions of psychopathology and cognitive development in ~10,000 children. Please check it out. Thanks Aaron Alexander-Bloch, Joe and other coauthors.👍 medrxiv.org/content/10.110…

New preprint explores how rare high-effect gene-coding variants (#CNVs) shape brain architecture and influence cognitive and socio-behavioral traits in adolescents (#ABCD). medrxiv.org/content/10.110…

Modern neuroscience leverages large datasets to embrace diversity missed in smaller studies, requiring revised modeling practices. Jakub Jakub Kopal discusses new analytic paradigms identifying nuanced drivers instead as key variables is crucial for impactful findings. #Diversity

Jakub Kopal 2nd talk at #OHBM2024 where he explored how copy number variations (CNVs), a significant source of genetic variation, play a crucial role in shaping the complex relationship between the brain and behavior.

Scientists when asked for their data "upon reasonable request"

Out now ! Key points: -Big neuroscience datasets are not big small datasets -Lion’s share of variation in brain measurements is not necessarily specific to a neuroscience questions -major brain disorders exhibit subpopulation-related divergences -Standard deconfounding tools,

New preprint! Strong genetic overlap between severe mental disorders and blood metabolic markers. Fascinating patterns: opposite effect directions of the markers on major depression versus bipolar disorder and schizophrenia. tinyurl.com/metaboPsych. #metabolicpsychiatry

Job alert!🚨 3-year postdoc position available at the Centre for Precision Psychiatry related to multimodal prediction algorithms for Alzheimer’s disease using data from genetics, neuroimaging, biomarkers and cognitive tests. Deadline Feb 6. Please share! jobbnorge.no/en/available-j…

Impressive and important work by Kevin O'Connell, Ole Andreassen and collaborators in PGC Consortium on the genomics of bipolar disorder published in nature 👏 ➡️ tinyurl.com/33krpxbd UiO - Det medisinske fakultet Oslounivsykehus med.uio.no/klinmed/englis…

"Copy number variants and the tangential expansion of the cerebral cortex". Work led by Zhijie Liao & Tomas Paus, out in Nature Communications, investigating the rare genetic architecture of the human cerebral cortex. doi.org/10.1038/s41467… Read content here: rdcu.be/eagHX

Understanding #Parkinsons subtypes is key to more targeted RCTs & better therapeutics! 🧠 Our new study finds that LRRK2 PD patients show milder cortical atrophy, with preserved temporal & occipital regions compared to sporadic PD. #LRRK2 #dataviz medrxiv.org/content/10.110…

#Multimorbidity is a pressing challenge in health care. We dissect its genetic architecture across mental and physical health, revealing shared and distinct links between brain structure, psychiatric disorders, and cardiometabolic disease. medrxiv.org/content/10.110…