🔥The 9th Round of Easy Loan, Earn $40 Reward is in progress❗️ ⏰ Promotion Period: January 15th - Feburary 15th, 2025 👉 Register now and check more details at gate.io/campaigns/358

Researchers at UC San Francisco Quantitative Biosciences Institute have reported how the kinetics of a molecular switch protein controls subsets of biological processes downstream of its 16 different functional protein-protein interactions. bit.ly/3pi2ihj

Now accepting applications for Rosetta Commons summer internships and postbac fellowships! Join our community and learn to design biomolecules and structural biology algorithms. #ProteinDesign #DeepLearning #DrugDesign #ComputationalBiology

How we maximize scientific reproducibility in Rosetta. Extensive test suite including 40 scientific benchmarks. Years of labor by Sergey Lyskov (Rosetta Test Engineer) and Julia Koehler Leman (Flatiron Institute) wrangling dozens of collaborating scientists! nature.com/articles/s4146…

Out today in bioRxiv, a new study from first author Chris Mathy, Tina Perica, and our collaborators in @BolonDan's lab, using deep mutational scanning to discover novel sites of allosteric regulation in a central GTPase. Check out Chris's tweetorial below! biorxiv.org/content/10.110…

Come work with us! We are hiring a specialist to do high-throughput testing of computationally designed proteins. Could be a BS/BA-level scientist looking to get experience before grad school, or someone looking to be long-term staff. Please share widely! aprecruit.ucsf.edu/JPF03924

In a new preprint, we describe an approach for multi-input gene regulation in mammalian cells, controlled by clinically approved drugs. Toward this goal, we engineer proteins of the nuclear hormone receptor family. biorxiv.org/content/10.110…

Super excited to share our model Frame2seq and our preprint “Structure-conditioned masked language models for protein sequence design generalize beyond the native sequence space” biorxiv.org/content/10.110… 1/n