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Yogesh Yogesh Kulathu gave a great talk on branched ubiquitin chains introduced by John Christianson Lab at the Oxford Ubiquitin Club. It seems the p97 system is again the main player in the story 😊.

Congratulations to our DPhil student Pauline Lascaux on her talk on the crosstalk between autophagy and DNA repair and the Grant Award (😀) at the 3rd FUSION Chromosomal Instability Conference in Dubrovnik, Croatia. fusion-conferences.com/conference/140

It is also great to see the current (Pauline) and ex-Ramadan lab members (Marta, Shudong John) attending one of the most prestigious conferences in Genome Stability in 2023 (Fusion, Dubrovnik, Croatia) and they all get along very well.

Congratulations to Cristiano Peron, our DPhil student, on his successful DPhil viva on the role of SPRTN protease in colorectal cancer therapy. We also thank his examiners, Profs Mark Middleton (left, Oxford), and Livio Trusolino (University of Torino).

There are two exceptional papers from the belilab and @stingele_lab labs on how cells cope with RNA-protein crosslinks: pubmed.ncbi.nlm.nih.gov/37951215/ and pubmed.ncbi.nlm.nih.gov/37951216/

The Lee Kong Chian School of Medicine (LKCMedicine) is recruiting a junior principal investigator at the level of Assistant Professor in Cancer and Stem Cell Biology. Please check the call: ntu.wd3.myworkdayjobs.com/Careers/job/NT… A great opportunity to start an independent research career.

The Lee Kong Chian School of Medicine (LKCMedicine) is recruiting a junior principal investigator at the level of Assistant Professor in Cancer and Stem Cell Biology. Please check the call: ntu.wd3.myworkdayjobs.com/Careers/job/NT…

DNA-PROTEIN CROSSLINKS in SINGAPORE Several post-doctoral positions will be available in my new lab at LKCMedicine/NTU in Singapore. Please check out these links: Senior Research Fellow: ntu.wd3.myworkdayjobs.com/Careers/job/NT… Research Fellow: ntu.wd3.myworkdayjobs.com/Careers/job/NT…

I am thrilled to announce that today, we launched a Cancer Discovery and Renegenartive Medicine Programme at LKCMedicine-NTU-Singapore: ntu.edu.sg/medicine/resea… We are recruiting new faculty members, but please feel free to reach out if you are interested in our research vision.

Congratulations to our DPhil student Pauline Lascaux, all our lab members, and collaborators worldwide NTU Singapore LKCMedicine OxfordOncology Ruđer Bošković Institute Vincenzo DAngiolella Nuno Raimundo on the role of nucleophagy in DNA repair. Please check: doi.org/10.1016/j.cell…

Oxford and NTU Singapore Study discovers new process for cells to repair DNA damage oncology.ox.ac.uk/news/oxford-an…

Hrvatski znanstvenici otkrili proces kojim se poboljšava postojeća terapija za karcinom debelog crijeva vecernji.hr/vijesti/hrvats…

Study discovers new process for cells to repair DNA damage ntu.edu.sg/news/detail/st…

Congrats to our former PhD student, Dr Susan Kilgas, on her first authored paper as a post-doc in Chowdhury Lab/@DanaFarberHarvard/ Harvard Medical School on the role of the long non-coding RNA NEAT1 in the regulation of 53BP1 function: nature.com/articles/s4146…

We have a tenure-track professorship position in Cancer Biology focusing on genome stability, the ubiquitin system, and the animal/zebrafish cancer models: ntu.wd3.myworkdayjobs.com/en-US/Careers/…

How does the SPRTN protease recognise DNA-protein crosslinks? This has now been resolved in our manuscript: biorxiv.org/content/10.110… The ubiquitin chains are the central regulators of SPRTN protease specificity and enzymatic activity towards DNA-protein crosslinks.