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#ICYMI: Ketone ester treatment in T2DM and HFpEF patients. @bborlaugmd Kristian Christensen Bertil Ladefoged @krisberghansen Nigopan Gopalasingam #AHAJournals

Important letter by Lars W Andersen on limitations of observational studies Observational studies and causal questions in resuscitation research– ... sciencedirect.com/science/articl…

Now published in the December edition of Anesthesiology 📖❄️ Explore the hemodynamic effects of elevated PEEP in cardiogenic shock in the paper (link in post ⬇️⬇️) or visit the Anesthesiology podcast (December 2024 edition, about 9 mins in) 🎧🦻 anesthesiology.libsyn.com

In patients with #cardiogenicshock 🫀worsening global longitudinal #strain #GLS associates with poor outcomes and surpasses conventional #echofirst parameters in prognostic value ☠️ #jacobjentzer ⁦Jae K. Oh⁩ academic.oup.com/ehjcimaging/ad…

Thrilled to announce that we have received ~2mill EUR from Helse- og omsorgsdep to conduct the STRONG@HOME trial at 7 sites in 🇳🇴🎉. Building on #STRONGHF, this trial will test efficacy and safety of rapid uptitration of #GDMT after HF hosp can be performed by digital follow-up 📲

In HFrEF patients, exogenous ketone body therapy improves cardiac function. But they have a short half life. Here we show prolonged ketosis and cardiac benefit with 1,3-butanediol in HFrEF patients🫀❤️‍🔥 Kristoffer Berg Hansen Oskar Hørsdal Nigopan Gopalasingam ahajournals.org/doi/10.1161/JA…

Thrilled to share our new study published in JCBFM (journals.sagepub.com/doi/10.1177/02…)! We show that targeting Na,K-ATPase-dependent Src kinase activation can prevent 🧠 hypoperfusion and exaggerated NVC in a an awake mouse model of familial hemiplegic #migraine. Here’s a short 🧵

This was a tough one. 40000 abstracts screened. Limited evidence for the use of calcium for Hyperkalaemia Pharmacological Interventions for the Acute Treatment of Hyperkalaemia: A Systematic Review and Meta-analysis - Resuscitation resuscitationjournal.com/article/S0300-… Lars W Andersen

#Biomarkers refine the #personalized management of cardiogenic #shock. 🔥 New state-of-the-art review led by Victor Galusko and ESC WG Thrombosis Chairperson 👉🏻 onlinelibrary.wiley.com/doi/10.1002/ej… CardioTomLuscher Vas Panoulas Christophe Vandenbriele European Society of Cardiology Journals King's College London Royal Brompton and Harefield European Society of Cardiology #CardioTwitter

1,3‐butanediol improves cardiac function in heart failure patients, offering potential for sustained ketosis therapy. #AHAJournals Halvor Guldbrandsen Nigopan Gopalasingam Kristian Christensen Oskar Hørsdal Kristoffer Berg Hansen Department of Cardiology Research AUH ahajrnls.org/3EbE2qr

Is #lactate friend or foe? Proud to share our data on the cardiovascular effects of lactate infusion 🫀 Looks a lot like the effects of #ketone infusion? 🤔 Nigopan Gopalasingam Nikolaj Rittig Department of Cardiology Research AUH rdcu.be/d6Ge7

We recently tested the hemodynamic effects of another monocarboxylate, butyrate, with similar molecular structure and function as #ketone bodies 🫀 @CasperHomilius Niels Moeslund Nigopan Gopalasingam Oskar Hørsdal Jacob Seefeldt sciencedirect.com/science/articl…

Proud to present the hemodynamic effects of lactate infusion in #cardiogenicshock at European Society of Cardiology #ACVC2025: Increased CO due to increased SV, enhanced ventriculo-arterial coupling and improved mitochondrial function 🫀 Full article published in Critical Care doi.org/10.1186/s13054…

Exciting experimental data from Alexander and Lasse from Department of Cardiology Research AUH presented today at European Society of Cardiology #ACVC2025 🫀 Ketone body 3-hydroxybutyrate may improve hemodynamics in #pulmonaryembolism Short chain fatty acid butyrate increases CO in healthy pigs (⬇️) doi.org/10.1016/j.lfs.…

Kristoffer Berg Hansen from Department of Cardiology Research AUH presenting data on metabolic profiling as predictor of mortality and neurological outcomes in out-of-hospital cardiac arrest patients at #ACVC2025 Published data below ⬇️⬇️ doi.org/10.1016/j.resu…

🚨NEW: The Trump Administration has destroyed a mural of Dr. Anthony Fauci at the NIH Headquarters. The painting was there to honor his work to combat infectious diseases and inspire other health officials. RETWEET if you stand with Dr. Fauci against the Trump Administration!

Now published in Basic Research in Cardiology 📑🚀 Infusion with #ketones improves hemodynamics and preserves mitochondrial and contractile function and in ischemic #cardiogenicshock 🐷🫀 doi.org/10.1007/s00395…

Great work by Peter Carøe Lind - even small changes in potassium is associated with increased risk of in-hospital cardiac arrest Potassium Levels and In-Hospital Cardiac Arrest: A Matched... : Critical Care Medicine journals.lww.com/ccmjournal/abs…