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Benchmarking of Small Molecule Feature Representations for hERG, Nav1.5, and Cav1.2 Cardiotoxicity Prediction #drugdiscovery pubs.acs.org/doi/10.1021/ac… Kris Laukens Wout Bittremieux (@[email protected]) #JCIM Vol64 Issue7 #MachineLearning #DeepLearning

A study of the cellular immunity of individuals co-infected with recurrent visceral leishmaniasis and HIV suggests that T cell unresponsiveness underlies visceral leishmaniasis chronicity NicklectedTropicalDiseases Institute of Tropical Medicine Antwerp NTDs @ ITM clinical sciences Kris Laukens Pieter Meysman Ana V. Ibarra-Meneses nature.com/articles/s4200…

Congratulations Charlotte Adams !

If you're interested in nanopore squiggles and microbes, you may find our database of raw #nanopore data interesting. Come talk to us at London Calling #nanoporeconf poster 58 (online 98), or learn more about our project via squidbase.org and reach out to us!!

Glad to finally be able to showcase our #TCR-#epitope annotation tool DETECT and the cool results we have gotten with it at the airr_community #AIRRC7 conference! And as of now you can use it yourself!

Romi Vandoren (University of Antwerp) introduces Adaptive Immune Receptor Repertoire-Wide Association Study (AIRRWAS), a framework to link TCR sequences to their target microbial species. #AIRRC7 Full agenda: tinyurl.com/airrcmeeting7

Vincent Van Deuren (University of Antwerp) analyzed the synovial fluid T-Cell Receptor (TCR) repertoire across different arthritis groups and T-cell subsets, to characterize the T-cells associated with HLA-B27 related spondyloarthropathies. #AIRRC7 tinyurl.com/airrcmeeting7

We have a doctoral position on computer science, data science and artificial intelligence with exciting applications in bioinformatics @uantwerpen. Thanks for spreading the news. Or even better, just apply! #doctoral #fellowship #bioinformatics #AI bit.ly/45C4Cmt

🧬 If you're at #ISMB2024 and interested in #nanopore sequencing data, come talk to me over lunch! (Poster 152) With squidbase.org we're collecting raw nanopore data to enable the development of new analysis tools.

🧐 "How does ImmuneWatch DETECT fit into my TCR analysis workflow?" Here's how: Our platform seamlessly integrates into your process, from TCR sequencing to specificity annotation, turning raw data into actionable insights. Discover more: immunewatch.com

What epitopes of your vaccine have triggered a T-cell response? 🧐 Learn how ImmuneWatch DETECT helps identify the exact epitopes driving T-cell responses using TCR sequencing data with a real-world SARS-CoV-2 vaccine example. youtu.be/ZzpTycXmkp4

Together with biomina and NSF@CMN, we hosted the #Nanopore Research Day at @UAntwerp! 🤩

The report on the open blinded TCR-epitope benchmark challenge is out! The analysis of the results turned out to be a bit more complicated than expected... Thanks again to all organizers and participants!

Gain comprehensive T Cell receptor analysis with iRepertoire and ImmuneWatch DETECT, an AI powered solution for antigen specificity. Contact us to learn more about this powerful predictive tool. Schedule a consultation at hubs.li/Q02TPy5v0 #AIprediction

tcrBLOSUM: An amino acid substitution matrix for sensitive alignment of distant epitope-specific TCRs • The study introduces tcrBLOSUM, a specialized amino acid substitution matrix designed for analyzing T-cell receptor (TCR) repertoires, improving the alignment and clustering

🚀 Advancing T-cell receptor (TCR) research! We developed tcrBLOSUM, a specialized substitution matrix for sensitive alignment of distant epitope-specific TCRs. Find out how our findings expand TCR analysis: doi.org/10.1093/bib/bb… #Bioinformatics #Immunology #AIRR

🚨 We're hiring! Join the University of Antwerp as a Postdoc in Molecular AI. 🔬 Develop AI for billion-scale metabolomics data & explore small molecules as life's building blocks. 📍 Antwerp, Belgium 🗓️ Apply now: bit.ly/4gpl4e7 #PostDoc #vacancy #bioinformatics

Massive effort by Kerry Mullan to recontextualize data is now out in Science Advances! We developed a new system STEGO to do a TCR-first analysis, and reanalyzed 12 studies and more than 500 000 individual T-cells. Supported by CZI Science ELIXIR Belgium doi.org/10.1126/sciadv…

The annual gathering of #Antwerp bioinformatics at the biomina Research Day, kicked off by Kris Laukens . Always amazing to see the varied #bioinformatics applications, from fish genomics to clinical biomarkers!