🔥The 9th Round of Easy Loan, Earn $40 Reward is in progress❗️ ⏰ Promotion Period: January 15th - Feburary 15th, 2025 👉 Register now and check more details at gate.io/campaigns/358

Out now in nature! Introducing our new method T cell ExTRECT that uses DNA sequencing data to directly quantify T cell fraction and its application in cancer. A quick thread 🧵 nature.com/articles/s4158… (1/20)

We are delighted to share our review ‘The translational challenges of precision oncology’ in Cancer Cell, co-authored with Chris Bailey under the guidance of Charles Swanton and our team 💪🏾 Tom Watkins Simone Zaccaria @MariamJHanjani shorturl.at/lnswJ 1/11

A privilege to present my work at the #IPSCC2022 and explore the beautiful city of Heidelberg. Thank you so much to the organisers for a fantastic first international conference experience! @ConferenceIpsc DKFZ

Very pleased to release our visualisation tool CloneMap into the wild. CloneMap is designed to provide visualisation of somatic clones in cancer or other tissues accounting for their size and phylogenetic relationships. github.com/amf71/cloneMap & biorxiv.org/content/10.110…

📰 Researchers from the Crick and UCL led by Cancer Research UK researcher Charles Swanton have revealed how air pollution can activate dormant cancer-causing mutations and increase the risk of lung cancer in never-smokers. Will Hill | Emilia Lim | Swanton Lab crick.ac.uk/news/2022-09-1…

Excited to share Refphase- a new R package for identifying haplotype-specific SCNAs and parallel copy number evolution in cancer. bioRXiv- tinyurl.com/525pp6av Tool- bitbucket.org/schwarzlab/ref… More below 👇 Tom Watkins Roland Schwarz Matt Huska Charles Swanton Nicholas McGranahan 🖥️🧬

Extremely proud of Ariana Huebner - passing her viva with flying colours (never in doubt!)...and many thanks to her examiners Florian Markowetz @NischalanP UCL Cancer Institute CRUKCOLcentre CRUK Lung Centre #cancerevolution #cancermetastasis

📢Our preprint ‘RNA allelic frequencies of somatic mutations encode substantial functional information in cancers’ is out today. Excited to tell you all about it, and our new tool, RVdriver: biorxiv.org/content/10.110… (1/8)

Today our important study on air pollutants in the promotion of lung cancer has been published in nature led by Will Hill Emilia Lim Clare Weeden Swanton Lab ...Thread below🧵nature.com/articles/s4158…

What a privilege to be part of this exciting cross-lab collaboration with outstanding scientists Kevin Ng Jesse Boumelha. All made possible thanks to our talented collaborators, funders, patients, and mentorship from Charles Swanton Julian Downward and George Kassiotis The Francis Crick Institute

Our paper together with Swanton Lab Charles Swanton ‘Genomic-transcriptomic evolution in lung cancer and metastasis’ comes out today nature. nature.com/articles/s4158… Read all about it 🚨👇 1/9

We're thrilled to share work on tumour evolution in 421 TRACERx lung cancer patients by Alex Frankell Michelle Dietzen Maise Al Bakir Emilia Lim Takahiro Karasaki Sophie Ward RajuVeeriah Emma Colliver Ariana Huebner Abi Bunkum Simone Zaccaria @MariamJHanjani Nicholas McGranahan🧵⬇️ nature.com/articles/s4158…

Our paper on genomic evolution in metastatic non-small cell lung cancer is out in Nature today! Extremely privileged and inspired to have been a part of this study alongside the fantastic Maise Al Bakir Ariana Huebner @CarlosEcolEvol Nicholas McGranahan

Delighted to present our paper on the evolutionary characterisation of lung adenocarcinoma (LUAD) morphology in the TRACERx cohort, published Nature Medicine led by Takahiro Karasaki david moore Nicholas McGranahan @MariamJHanjani Swanton Lab nature.com/articles/s4159…

CONIPHER enabled us to identify expanded subclones dominating an entire sample. Recent subclonal expansions were found to be associated with poor outcome in primary tumours, and subclones seeding metastasis were found to dominate several regions of the primary tumour. 10/n

Our method for reconstructing tumour phylogeny, CONIPHER, is now out in Nature Protocols! We used CONIPHER to reconstruct over 400 trees in TRACERx. Thanks to co-authors Ariana Huebner Abi Bunkum Emma Colliver Alex Frankell and supervisors Nicholas McGranahan Simone Zaccaria Charles Swanton!

If you can stomach the tree based puns that Nicky definitely wrote himself, then this is a really interesting thread about a very cool new computational tool which took a ton of work used in all of the recent set of TRACERx papers.

.Siddhartha Mukherjee reports on groundbreaking research into a special class of carcinogens that create the contexts where cancer ultimately can thrive. nyer.cm/Gam7N8G

📢📢 We're hiring! Just finished your PhD? Come help us figure out how cancers evolve and develop diagnostics. You'll work in a multi-lab team Early Cancer Institute, University of Cambridge/The Crick and lead a stunning project on lung cancer. Flexible start date to Oct. Pls RT! jobs.cam.ac.uk/job/45357/

Last day to apply to join Charles Swanton and Swanton Lab as a postdoc! Wet lab position, amazing colleagues and a chance to work at the world leading The Crick Apply here 👇 tinyurl.com/ye263rdv