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A doctor took cancerous tissue from the uterus of a Black woman (Henrietta Lacks) w/o her consent. And scientists have used her cells and profited from it while her family (tricked & traumatised) have yet to be compensated. With your silence you have chosen a side.

Antibiotics fuelled the growth of the twentieth century’s most profitable pharmaceutical companies, and are one of society’s most desperately needed classes of drug. Yet the market for them is broken. go.nature.com/2YgEdt3

How lipids are transported in Gram-negatives has got a lot of attention lately. Here is a paper from my lab that we hope helps the field as that was the driving force behind this work. Shout out to Matthew Powers and Brent Simpson for their dedication. elifesciences.org/articles/56571

I continue to be amazed by the contribution of physiological bicarbonate to antibiotic action. Very proud of this effort led by Maya Farha. Good fun as always to work with @agmcarthur laboratory. pubs.acs.org/doi/10.1021/ac…

If your antibiotic discovery strategy involves targeting the outer membrane of Gram-negs, it's good to know that pesky resistance mechanisms may not spoil the party. Lovely work here by Craig MacNair who takes a thorough approach this question. mbio.asm.org/content/11/5/e…

With growing evidence that carbon utilization is an Achilles heel for many pathogens, Maddy led a genome-scale look at the growth of E. coli in 30 carbon sources. Shout out to the Karp Lab and the new metabolic modelling capabilities of BioCyc&Pathway Tools.

A great review on one of my favourite topics! So much potential in this field 🦠 Border Control: Regulating LPS Biogenesis cell.com/trends/microbi…

I downloaded this mindfulness app approx. two weeks ago and have zero regrets! It’s free for this year and the offer ends at the end of this month. More details here ⬇️

So excited to share the result of collaborating with an amazing team! Couldn't have done it without their expertise, tremendous support, and hard work!

Join us on Wednesday, March 10, for our next #glycotime webinar! Speakers Kamil Godula (UC San Diego) & Kristina Klobucar (McMaster University) will cover 1️⃣ stem cell differentiation using glycomaterials, and 2️⃣ antibacterials discovery platform. Registration: us02web.zoom.us/meeting/regist… #ACSCARB

Nice work here by Sara El Zahed, Shawn French and team to take a hard look at the chemistry behind bacterial drug efflux. aac.asm.org/content/65/4/e…

Great fun to describe our journey in chemical and systems biology of bacteria for Accounts of Chemical Research. So fitting to co-author this work with my hugely talented Research Associates Maya Farha and Shawn French who have blazed this trail. pubs.acs.org/doi/full/10.10…

Types of Microbiology paper. 🔬

Great fun collaborating with the Hung and Magolan groups on the discovery of new small molecule probes of the Gram-negative outer membrane. Tremendous leadership by Kristina Klobucar and a huge effort by J-P Côté! pubs.acs.org/doi/10.1021/ac…

I’ve been fantasizing about this tweet for ages and finally I can say I am SO EXCITED to share with y’all the preprint for my first first author research paper!!!! 😁🎉 Here @gerryiidr and I correct the literature surrounding the “resistance enzyme” CrpP aac.asm.org/content/aac/ea…

Check out our new review on compounds that potentiate antibiotics against Gram-negative bacteria by perturbing the outer membrane, out in Current Opinion in Chemical Biology Elsevier Chemistry Eric Brown: authors.elsevier.com/c/1e6Gy4sz6MBA…

Researchers from the Brown Lab and Magolan Lab of the McMaster IIDR at McMaster University have identified a series of metergoline analogues as interesting new leads for antibiotic development. Check it out in ACS Med. Chem. Lett.: go.acs.org/db

My first review with Silvia Cardona is out in FEMS Reviews! 2+ years of brainstorming put on paper 😊 TLDR: bacterial essential genes are not all equal and this can be used to prioritize #antibiotic development. A thread 1/9 academic-oup-com.uml.idm.oclc.org/femsre/advance…