
Lars Barquist
@lbarquist
Assistant Prof @UofT, research group leader @Helmholtz_HIRI. Pathogen systems biology / informatics / functional genomics. Coastal New Hampshirite. Drink Moxie.
ID: 784703255427284993
https://scholar.google.com/citations?hl=en&user=9MYn5q8AAAAJ&view_op=list_works&sortby=pubdate 08-10-2016 10:33:30
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Interested in predicting AMR in bacteria? We show ignoring phylogenetic structure in genome collections leads to overly optimistic evaluations of machine learning methods for AMR prediction. With Yanying Yu and Nicole Wheeler. biorxiv.org/content/10.110…

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🚀 New Paper Alert! 🚀 𝐑𝟐𝐃𝐓: a comprehensive platform for visualising RNA secondary structure Check it out in Nucleic Acids Res: academic.oup.com/nar/article/53… Here’s why you should give it a try 🧵👇





Very excited about our latest combining advanced cell culture, transposon-insertion sequencing, and statistical modeling to map Shigella virulence determinants in organoid models. Great collaboration w/ Maria Letizia Di Martino Sellin Lab, out in Nature Genetics nature.com/articles/s4158…

Large-scale organoid models, combined with genome-wide mutagenesis screening, reveals virulence factors required for Shigella colonization Maria Letizia Di Martino Nature Genetics Sellin Lab Lars Barquist nature.com/articles/s4158… nature.com/articles/s4158…


A study in Nature Genetics establishes the comprehensive genome-wide map of Shigella genes required to infect human intestinal epithelium. go.nature.com/3ZySYa8
