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Slightly late, and to be updated with the results of today's TTM2 biomarker results, today's Paper of the Day is: Biomarkers for neuroprognostication after out-of-hospital cardiac arrest criticalcarereviews.com/latest-evidenc…

Never fails to impress every year… the venue and the conference! 😄👏Critical Care Reviews #CCR25

Our thought and analysis in the work of the UK-ROX team👏 UK-ROX Trial Critical Care Reviews #FOAMed #POCUS #FOAMcc #Meded #MedX Presented at the tremendous #CCR25 meeting

Is Days alive AND at home AND without support too complex a primary outcome (and despite being highly relevant to patients) would it be responsive to the intervention at question ? #CCR25 #NOTACS

#CCR25 #NOTACs In general, have we over-adopted HFNO in critical care, leaning heavily on its physiological benefits?

ICU-acquired weakness and cardiogenic shock in patients requiring mechanical support, highlighting biomarkers and outcomes. Critical Care Reviews #FOAMed #POCUS #FOAMcc #CCR25 #Medx criticalcarenorthampton.com/2025/06/12/bio…

Presented at #CCR25: In a cluster-randomized, crossover trial, hospital-wide use of lactated Ringer’s solution as compared with normal saline did not alter the incidence of death or hospital readmission within 90 days. Full trial results: nej.md/45SaEBs

Another super cluster crossover trial at #CCR25 - the FLUID trial (looking at Ringers lactate vs normal saline - at the system level). 1/3 See paper here … nejm.org/doi/full/10.10…

Comparison of lactated Ringer’s solution and normal saline for IV therapy on ICU. #FOAMed #POCUS #FOAMcc #CCR25 #MedX criticalcarenorthampton.com/2025/06/12/har… Critical Care Reviews IMCrit

🩸Among adults undergoing cardiac surgery, ANH did not reduce the number of patients receiving allogeneic red-cell transfusion. These are the findings of the #ANHtrial, our latest multicenter RCT, just presented at #CCR25 and published in NEJM. 📎 nejm.org/doi/full/10.10…

Did acute normovolaemic haemodilution prior to cardiac surgery improve morbidity? #CCR25 Critical Care Reviews #FOAMed #POCUS #FOAMcc #Medx criticalcarenorthampton.com/2025/06/12/anh… IMCrit

Did high flow nasal oxygen therapy after cardiac surgery improve outcomes? NOTACS trial #FOAMed #POCUS #FOAMcc #Medx #CCR25 Michelle Smyth Brian Burns Paul Young

🔎 The #PRINCEtrial: 👥 1,100 pts undergoing non-cardiac surgery 💡Remote Ischemic Preconditioning (3x5 min cuff inflation/deflation) 💉 Comparison: Sham RIPC (cuff placed, not inflated) 🎯 Outcome: Postop cardiac troponin release #CCR25 Critical Care Reviews

#CCR25 #PRINCEtrial Is it possible that any potential benefit of RIPC was offset by a longer duration of general anaesthesia ?

Could hear a 📌 drop during the Johns Hinds lecture by John Myburgh celebrating humanity, integrity and excellence. Fantastic! Critical Care Reviews #CCR25 Josephine Hinds

It’s a wrap! Another great Critical Care Reviews meeting. #CCR25

Central line simulation trainers - recommendations please!