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EMBO members' new laboratory game: Find your PI.😉

The isolation of the BRCA1 gene 30 years ago ushered in the era of genetic testing for breast and other cancers, launched a long-lasting patent battle and eventually led to a tailored cancer therapy go.nature.com/48s6PSU

Welcome to the newly elected EMBO Members Oliver Hobert Columbia Biological Sciences, Valérie Borde Borde Lab, Lumír Krejci Masaryk University, Ivan Matić The Matic Lab, Ewelina Knapska Ewelina Knapska, Steven West @XRNchew, Ita Gruić-Sovulj, Martin Howard John Innes Centre and Paola Scaffidi! #EMBOat60

Hana Polášek-Sedláčková Hana Sedlackova, former member of our lab, presents her work as an EMBO Installation grantee in Heidelberg at the Meeting of the EMBO Communities.

Cheers to the TRIAD team (CMAzzalin Lab George Garinis and Lumír Krejčí) for hosting a really wonderful meeting in Lisbon! Till the next time…

Our students attend the annual PhD Conference in Biomedical Sciences of our home Department of Biology.

We had an amazing time this week hosting our partners from the TRIAD project, George Garinis and Krejci lab (LORD), for our 1st in person meeting!

We are grateful to have received a 3-year research grant from the Czech Science Foundation, in collaboration with Karel Kubíček KarelK77 , to study the structure and biological role of the RAD51 protein.

Our new website needs photos of wild scientists in their sanctuary 😀😀

Our department enjoyed the first snow of the winter 🙃

Christmas lunch in our lab. Merry Christmas 🎄

Happy New Year 2025

"Discovery of new inhibitors of nuclease MRE11" is a collaborative work with Kamil Paruch from International Clinical Research Center and Masaryk University, Institute of Molecular Genetics and Loschmidt Laboratories, Masaryk University which has been published in European Journal of Medicinal Chemistry. doi.org/10.1016/j.ejme…

Excited to share our findings in Nature Communications. We have expanded our understanding of telomere maintenance and genome stability through the RECQ4-MUS81 interaction, shedding light on its potential role in disease development. #GenomeStability muni.cz/go/186ece

Huge congratulations to our colleague Raghib A. on successfully defending his dissertation on RECQ4–MUS81 interaction and earning his PhD! Wishing you all the best as you begin this exciting new chapter in Germany, Raghib! 🙂

Happy to see our latest collaborative manuscript published in Molecular Cell! We hope this work will substantiate the role of biomolecular condensates in the regulation of DNA repair and chromatin organization. muni.cz/go/447969