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Bacteria can affect outcome of LDH assay used to measure cytotoxicity. Description of mechanisms + alternative approach proposed by Sara Van den Bossche (her first 1st author paper, congrats!) Eva Vandeplassche Lisa Ostyn @tcoenye Aurélie Crabbé frontiersin.org/articles/10.33…

Does the mode of dispersion determine the properties of dispersed Pseudomonas aeruginosa #biofilm cells? It took a while to get this publishede but here it is: sciencedirect.com/science/articl… (spoiler: the answer is yes - to some extent) @jasperwille92 @tcoenye

Yesterday evening we got an early visit from Santa. Did Santa look like Aurélie Crabbé and @tcoenye? #maybe

Last big experiment done! Happy holidays from all of us!

Annual lab tradition on Epiphany (in Dutch: 'drie koningen') in a slightly (well...) modified and corona-proof version - and @tcoenye found the king! (meaning he gets to buy the three kings' cake next year). You can read all about this tradition here en.wikipedia.org/wiki/King_cake

Very proud and happy to welcome Yuming Cai to our team at UGent Pharmacy ! Yuming obtained a highly competitive fellowship from Marie Skłodowska-Curie Actions and will work on using repurposed drugs for antibiofilm treatment.

If your are interested in applying for an MCSA Postdoctoral Fellowship, UGent offers an extensive training program/master class. Don't hesitate to get in touch! ugent.be/en/research/fu…

Great to see this paper for which PhD student Mona Bové has worked so hard is now out! Key message: quorum sensing inhibitor C-30 is not ‘evolution-proof’ and quickly becomes ineffective as potentiator of tobramycin activity against P. aeruginosa #biofilms aac.asm.org/content/early/…

Final day of #ECFS2021 kicking off with a 'What is new in microbiology' session including a talk by Aurélie Crabbé on microbial interactions.

This is not how you want to see your lab - but once all this is done there will be a fancy new ceiling, new water lines, airco and sun shades. That thought keeps us going ;-) #ugent #investinthefuture

An afternoon of bowling during the #ugent sports afternoon. #teamlpm

Today we welcome Merel Wauters in our group at UGent Pharmacy. Merel will work with Aurélie Crabbé on nanobody-based treatments for P. aeruginosa induced inflammation.

Xuerui Bao's first 1st author paper as member of our group - on the antibiotic potentiating activity of certain carbon sources- now published. Congratulations! (and thx to Symcel for the nice collaboration!) journals.asm.org/doi/10.1128/AA…

Mona Bové and @tcoenye investigated the antivirulence activity of the fosmidomycin derivative FR900098 in Burkholderia cenocepacia (alone and combined with cefta). Data show its activity is maintained during in vivo experimental evolution in C. elegans microbiologyresearch.org/content/journa…

Our paper on the role of Rothia in limiting inflammation in the respiratory tract now published (erj.ersjournals.com/content/59/5/2…) and ERS publications devoted an editorial to it: erj.ersjournals.com/content/59/5/2…. Charlotte rigauts @tcoenye Aurélie Crabbé LMPH @ UAntwerpen

This afternoon (WS13) Sara Van den Bossche wil present her work on diversity in AMR of P. aeruginosa CF sputum isolates #ECFS2022 (supervisor: Aurélie Crabbé)

In the #ECFS2022 session 'Impact of biofilm in CF' that starts at 10.30 @tcoenye will discuss innovative approaches to treat #biofilm infections. Also in that session: Catherine Armbruster, Claus Moser and Jane Gross. Room Dock 1!

Today Sara Van den Bossche will defend her PhD work at UGent Pharmacy, she has worked on the impact of the #CF lung microenvironment on activity of antibiotics against Pseudomonas aeruginosa. Main promotor is Aurélie Crabbé.

Happy to announce we received funding from #ugent to continue our work on development of more in vivo-like media and use of microcalorimetry to study #biofilm related infections. This will allow us to continue collaboration with Symcel and to expand to other disease areas.

It's PhD time again. Today Xuerui Bao will present her PhD work in the public defense at UGent Pharmacy. Guess what - it's about #biofilms! 😁 Promotors are @tcoenye and Aurélie Crabbé, chair is @KatrienRemautUG.