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Our newest paper on murine ligaments in PTOA and mechanical changes available on BioRxiv. Congratulations Lorenzo Ramos-Mucci, PhD @KrisDaout Eithne Comerford 🇮🇪🇺🇦🇪🇺 Institute of Life Course and Medical Sciences Craig Keenan

To say we are really excited about this funding is an understatement! We can't wait to work together to establish training & deliver ancestrally diverse atlases of musculoskeletal tissues. Adam Cribbs Vikas Khanduja Sub-Saharan African Musculoskeletal Network Christopher Buckley ndorms.ox.ac.uk/news/chan-zuck…

NDORMS researchers Sarah Snelling, Adam Cribbs, Christopher Buckley and Mathew Baldwin are building a diverse musculoskeletal atlas of healthy tissues. The work is being funded by Chan Zuckerberg Initiative ndorms.ox.ac.uk/news/chan-zuck…

To help develop better treatments for those suffering from tendon tears, #ECR Sarah Snelling’s lab builds tissue atlases of the human tendon to serve as a reference so they can develop biomaterial-based treatments. #SciComm #Science

Congrats Paula Sarmiento & Lorenzo Ramos-Mucci, PhD on publication of "Pipelines to human tendon transcriptomics" This was fun to be part of & very much a team effort with joint 1st & last authors. It's also relevant to tissues beyond tendons! Dr. Dr. Dianne Little 🇺🇦 🏳️‍🌈 Journal of Orthopaedic Research® onlinelibrary.wiley.com/doi/10.1002/jo…

Hot off the press! A lot of fun to write with Sarah Snelling Paula Sarmiento Lorenzo Ramos-Mucci, PhD - tips to navigate the challenges of human #tendon transcriptomic studies. ORS Tendon Section Orthopaedic Research Society Journal of Orthopaedic Research® onlinelibrary.wiley.com/doi/10.1002/jo…

I'm late to the party, but wanted to share our newest perspective review on tendon transcriptomics! Learned a lot working with Paula Sarmiento and many thanks to Sarah Snelling and Dr. Dr. Dianne Little 🇺🇦 🏳️‍🌈 for the encouragement. onlinelibrary.wiley.com/doi/10.1002/jo…

Our work “Single-cell eQTL mapping identifies cell type-specific genetic control of autoimmune disease” just published in Science Magazine. The work started with the creation of the OneK1K cohort, consisting of scRNA-seq data on PBMCs from ~1000 donors science.org/doi/10.1126/sc… 🧵

Our latest publication is finally online!!! Well done Lorenzo Ramos-Mucci, PhD We describe changes in histological and mechanical properties with post traumatic osteoarthritis in vivo model. Institute of Life Course and Medical Sciences Versus Arthritis Eithne Comerford 🇮🇪🇺🇦🇪🇺 @KrisDaout School of Engineering LivUni rdcu.be/cPCfU

The mechanism of action of LNA043, a disease-modifying #osteoarthritis treatment candidate, is characterized in preclinical studies and through transcriptomic profiling of osteoarthritis patient cartilage from a phase 1 trial #OA #NIBR Novartis Science nature.com/articles/s4159…

We are thrilled to share our pre-print: “Single nucleus and spatial transcriptomic profiling of human healthy hamstring tendon” biorxiv.org/content/10.110… Lorenzo Ramos-Mucci, PhD Claudia Paul Alina Kurjan, DPhil Chinemerem Hulley_Lab Steve Gwilym Adam Cribbs mathew baldwin Sarah Snelling

Not very often scientists are featured in the newspaper, even if it is just a brief mention of the bone research we are doing at Relation. We work hard to have a lasting impact on the patients. Check out the article on The Times and The Sunday Times: thetimes.co.uk/article/office…

Pls RT! We are hiring a senior computational biologist to work on large sc/spatial datasets of human brain cancer. High potential for career dev & long term opportunities with the lab. We are drowning in cool data & you get to look at pretty ST as a bonus tinyurl.com/d3kwc74x

Transformers for cell segmentation in spatial transcriptomics nature.com/articles/s4159…

We are thrilled that our paper on healthy hamstring tendons is finally out in FASEB Journal! faseb.onlinelibrary.wiley.com/doi/10.1096/fj… Congratulations to the amazing team that worked on this Sarah Snelling, Adam Cribbs, mathew baldwin, Lorenzo Ramos-Mucci, PhD, Alina Kurjan, DPhil, Claudia Paul, and many more!

Have you ever wondered which single cell/spatial omic technology to use? There's lots of methods developed in academia, but no review of marketed products. Check the scTrends.org (sctrends.org) commentary in Nature Biotechnology by Jake P. Taylor-King & Adam Cribbs

Today is the go live day for scTrends.org! A consortium to both review *commercial* technologies, but also study market trends to assess angles for how technologies may differentiate themselves.

Have you ever wondered which single cell/spatial omic technology to use? Excited to share the scTrends Consortium's first report on single-cell and spatial genomics tech! Check out our comment in Nature Biotechnology! #Genomics #Biotech #scTrends nature.com/articles/s4158…

Want to get involved in scTrends.org ? Read about the #livingreview concept here: sctrends.org/p/coming-soon

Our latest scTrends.org article is now in Cell Genomics: cell.com/cell-genomics/… Paired with this is our end of year round up: sctrends.org/p/end-of-year-… Get in touch if you want to be involved!