
Melnick Lab
@labmelnick
Investigating epigenetic and transcriptional dysregulation in hematological malignancies 🧬
ID: 1128350124835573765
https://melnicklab.org/ 14-05-2019 17:23:28
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890 Followers
188 Following

Amazing lecture at Weill Cornell from Vijay Sankaran Vijay Sankaran!! Elegant and brilliant - thanks for visiting us!




During antibody affinity maturation in germinal centers (GCs), many defective B cells die by apoptosis. These cells are removed by tingible body macrophages (TBMs). Here, we describe their origin and function. 🧵Neta Gurwicz doi.org/10.1084/jem.20… Journal of Experimental Medicine

Read this week's Cancer Discovery #ResearchWatch: Mutations in BTG1 Promote Germinal Center #Bcell Malignant Transformation, a summary of the paper by @coraline_mly, Melnick Lab et al. bit.ly/3XKybgL Weill Cornell Medicine





And please stop by our posters on Sunday and Monday #ASH2023 to learn about more amazing work on DLBCL models and biology! including cool new data by Laurianne Scourzic with Effie Apostolou lab





and co-published story by Michael Green, PhD -- great time for epigenetics in the B cell lymphoma field!

Researchers identify mechanisms that can transform follicular lymphoma into an aggressive form of cancer in some patients. Findings from a team led by Dr. Ari Melnick (Melnick Lab) of Weill Cornell Medicine Meyer Cancer Center suggest potential for new therapeutic strategies. bit.ly/3TsJucs


We are on the cover of Cancer Cell! Check out our latest story on ARID1A and BAF remodeling complex in lymphoma: doi.org/10.1016/j.ccel… Led by Darko Barisic Christopher Chin. WCM Lymphoma Weill Cornell Medicine Meyer Cancer Center Weill Cornell Medicine Cancer Cell


Thrilled to share we are National Cancer Institute R00-funded. 🥳 Looking for computational biologists or bioinformaticians. 👩💻👨💻 We have many exciting projects on the role of chromatin remodelers in blood cancers. 🩸🦀 Please share/DM/email if relevant. Our latest story: cell.com/cancer-cell/ab…
