
Costanzo’s Lab
@labvincenzo
We study basic mechanisms of genome stability maintenance altered in cancer
ID: 1804087104168681472
21-06-2024 09:41:21
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208 Followers
647 Following





Deadlines are approaching for Keystone Symposia #DNAReplication Gaps, Cancer and Disease, this April in Daejeon! See scholarship, abstract and discount reg dates: keysym.us/KSDNARep25 #KSDNARep25








Thrilled to share our latest work at Science Advances. Great collab with Costanzo, Masson, Freire and Reyes labs. HMCES corrupts replication fork stability during base excision repair in homologous recombination–deficient cells | Science Advances science.org/doi/10.1126/sc…

🙏 Thank you, Pavel Moudrý, Costanzo’s Lab, and Evident, for fantastic collaboration! Special thanks go to the exceptionally talented postdoc Paolo Fagherazzi and the brilliant image analysis specialist Timo Diekmann for their extraordinary efforts! 🙏

It's out! nature.com/articles/s4158… Structure of the two RAD52 rings forming a spool-like structure at replication fork, rearranging and protecting the fork. Tour-de-force work by Masa Honda and Ali Razzaghi and wonderful (as usual) collaboration with Pietro Pichierri 🇮🇹🇪🇺 @[email protected] 's lab.

Truly honored that my career path and laboratory have been featured in the 'Cell Scientist to Watch' interview series. A huge thank you Sara Morais da Silva and J Cell Science for this wonderful opportunity 🙏





🚨 Hot off the press!!! Wanted to share this to celebrate the momentous achievement from the Giunta Lab and for the human centromere / genomics communities as a whole... more posts to come next week but for now, happy Fourth & happy reading ❤️🧬💻 science.org/doi/10.1126/sc…